Systematic review and meta-analysis of risk of gestational diabetes in women with preconception mental disorders.
Systematic review and meta-analysis of risk of gestational diabetes in women with preconception mental disorders.
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患有孕前精神障碍的女性妊娠期糖尿病风险的系统回顾和荟萃分析。
DOI：
10.1016/j.jpsychires.2022.03.013
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发表时间：
2022
影响因子：
4.8
通讯作者：
Wilson CA
中科院分区：
文献类型：
--
作者：
Wilson CA
在2型糖尿病和精神障碍之间有一个明确的双向关联，并且有新的证据表明妊娠糖尿病（GDM）妇女围产期精神障碍的风险增加。然而，怀孕前的精神障碍与随后的GDM风险之间的关系仍然相对未被探索。这是一项对一系列孕前精神障碍女性发生GDM风险的系统综述和荟萃分析。同行评议的文献测量GDM和孕前情绪、焦虑、精神病和饮食失调的几率。使用检查表评估偏倚风险。两名独立审查人员参与了调查。22项观察性研究符合纳入标准；大多数是来自讲英语的高收入国家的回顾性队列。14项研究存在高偏倚风险。有证据表明，精神分裂症女性患GDM的风险增加（综合OR为2.44；95% CI为1.17,5.1；5项研究），神经性厌食症女性患GDM的风险降低（综合OR为0.63；95% CI为0.49,0.80；5项研究）。有一些有限的证据表明双相情感障碍女性的风险增加。荟萃分析没有证据表明与孕前抑郁或神经性贪食有关。关于焦虑症的meta分析研究不足。这篇综述表明，许多孕前精神障碍与GDM没有显著的相关性，但患有精神障碍的女性是GDM的一个独特易感群体。早期发现和管理GDM可以改善这些妇女及其子女的身心健康结果。
There is a well-established bidirectional association between Type 2 diabetes and mental disorder and emerging evidence for an increased risk of perinatal mental disorder in women with gestational diabetes (GDM). However, the relation between mental disorder prior to pregnancy and subsequent risk of GDM remains relatively unexplored. This is a systematic review and meta-analysis of the risk of GDM in women with a range of preconception mental disorders. Peer-reviewed literature measuring odds of GDM and preconception mood, anxiety, psychotic and eating disorders was systematically reviewed. Risk of bias was assessed using a checklist. Two independent reviewers were involved. 22 observational studies met inclusion criteria; most were retrospective cohorts from English speaking, high income countries. 14 studies were at high risk of bias. There was evidence for an increased risk of GDM in women with schizophrenia (pooled OR 2.44; 95% CI 1.17,5.1; 5 studies) and a reduced risk of GDM in women with anorexia nervosa (pooled OR 0.63; 95% CI 0.49,0.80; 5 studies). There was some limited evidence of an increased risk in women with bipolar disorder. There was no evidence for an association with preconception depression or bulimia nervosa on meta-analysis. There were insufficient studies on anxiety disorders for meta-analysis. This review indicates that there is not a significant risk of GDM associated with many preconception mental disorders but women with psychotic disorders represent a group uniquely vulnerable to GDM. Early detection and management of GDM could improve physical and mental health outcomes for these women and their children.
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影响因子：
6.6
作者：
Wilson, Claire A.;Santorelli, Gillian;Howard, Louise M.
通讯作者：
Howard, Louise M.
妊娠期间抗精神病药物的使用和妊娠糖尿病的风险：系统评价和荟萃分析
影响因子：
6.9
作者：
Z. Wang;I. Wong;Kenneth K C Man;B. Alfageh;P. Mongkhon;R. Brauer
通讯作者：
R. Brauer
影响因子：
2.6
作者：
Kitai, Toshihiro;Komoto, Yoshiko;Takemura, Masahiko
通讯作者：
Takemura, Masahiko
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
16.2
作者：
Kan C;Silva N;Golden SH;Rajala U;Timonen M;Stahl D;Ismail K
通讯作者：
Ismail K