Evolution and phyletic distribution of two-component signal transduction systems.

Evolution and phyletic distribution of two-component signal transduction systems.
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DOI:
10.1016/j.mib.2009.12.011
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发表时间:
2010-04
影响因子:
5.4
通讯作者:
Zhulin, Igor B.
Zhulin, Igor B.
中科院分区:
生物学2区
文献类型:
--
作者:
Wuichet, Kristin;Cantwell, Brian J.;Zhulin, Igor B.

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双组分信号转导系统在原核生物中非常丰富。它们使细胞能够调整多种细胞功能以应对不断变化的环境条件。虽然数量少得多,但在低等真核生物和植物中也发现了这些系统,它们似乎控制着一些非常特殊的功能。细菌中的双组分系统是从简单得多的单组分系统进化而来的,带来了细胞外与细胞内感应的优势。我们回顾了建立双组分系统起源的报告,并记录了它们在主要生命谱系中的发生。
Two-component signal transduction systems are abundant in prokaryotes. They enable cells to adjust multiple cellular functions in response to changing environmental conditions. These systems are also found, although in much smaller numbers, in lower eukaryotes and plants, where they appear to control a few very specific functions. Two-component systems have evolved in Bacteria from much simpler one-component systems bringing about the benefit of extracellular versus intracellular sensing. We review reports establishing the origins of two-component systems and documenting their occurrence in major lineages of Life.
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