Systems biology approaches to identify developmental bases for lung diseases.
Systems biology approaches to identify developmental bases for lung diseases.
复制标题
系统生物学方法以识别肺部疾病的发育基础。
DOI：
10.1038/pr.2013.7
复制
发表时间：
2013-04
影响因子：
3.6
通讯作者：
Mariani, Thomas J.
中科院分区：
文献类型：
--
作者：
Bhattacharya, Soumyaroop;Mariani, Thomas J.
A greater understanding of the regulatory processes contributing to lung development could be helpful to identify strategies to ameliorate morbidity and mortality in premature infants and to identify individuals at risk for congenital and/or chronic lung diseases. Over the past decade, genomics technologies have enabled the production of rich gene expression databases providing information for all genes across developmental time or in diseased tissue. These data sets facilitate systems biology approaches for identifying underlying biological modules and programs contributing to the complex processes of normal development, and those that may be associated with disease states. The next decade will undoubtedly see rapid and significant advances in redefining both lung development and disease at the systems level.
登录
查看更多内容
DOI：
10.1165/rcmb.2008-0114oc
发表时间：
2009-03-01
影响因子：
6.4
作者：
Bhattacharya, Soumyaroop;Srisuma, Sorachai;Mariani, Thomas J.
通讯作者：
Mariani, Thomas J.
影响因子：
10
作者：
Brehm JM;Hagiwara K;Tesfaigzi Y;Bruse S;Mariani TJ;Bhattacharya S;Boutaoui N;Ziniti JP;Soto-Quiros ME;Avila L;Cho MH;Himes B;Litonjua AA;Jacobson F;Bakke P;Gulsvik A;Anderson WH;Lomas DA;Forno E;Datta S;Silverman EK;Celedón JC
通讯作者：
Celedón JC
影响因子：
3.9
作者：
Bhattacharya, Soumyaroop;Mariani, Thomas J.
通讯作者：
Mariani, Thomas J.
DOI：
10.1164/rccm.200907-1063oc
发表时间：
2010-01-01
影响因子：
24.7
作者：
Kho, Alvin T.;Bhattacharya, Soumyaroop;Mariani, Thomas J.
通讯作者：
Mariani, Thomas J.
影响因子：
1.2
作者：
Liu, Yuru;Hogan, Brigid L. M.
通讯作者：
Hogan, Brigid L. M.