iPath3.0: interactive pathways explorer v3.

iPath3.0: interactive pathways explorer v3.
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DOI:
10.1093/nar/gky299
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发表时间:
2018-07-02
影响因子:
14.9
通讯作者:
Yamada T
Yamada T
中科院分区:
生物学2区
文献类型:
--
作者:
Darzi Y;Letunic I;Bork P;Yamada T

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iPath3.0(pathways.embl.de)是一个用于细胞通路可视化和分析的网络应用程序。它是免费提供的,对所有人开放。目前,它基于四个KEGG全球地图,将多达158个传统KEGG通路地图,192个KEGG模块和其他代谢元素汇总到一个连接和手动策划的代谢网络中。用户可以完全自定义这些网络,并通过其重新设计的,快速和轻量级的界面交互式地探索它们,该界面突出了多组学数据中的一般代谢趋势。它还提供不同级别的详细导航,以帮助用户进一步研究这些趋势并最终发现新的生物学见解。该版本引入了对多个实验条件和时间序列数据集的支持、用于生成定制数据的工具、编程访问和免费用户帐户系统,以进一步简化其工作流程。
iPath3.0 (http://pathways.embl.de) is a web-application for the visualization and analysis of cellular pathways. It is freely available and open to everyone. Currently it is based on four KEGG global maps, which summarize up to 158 traditional KEGG pathway maps, 192 KEGG modules and other metabolic elements into one connected and manually curated metabolic network. Users can fully customize these networks and interactively explore them through its redesigned, fast and lightweight interface, which highlights general metabolic trends in multi-omics data. It also offers navigation at various levels of details to help users further investigate those trends and ultimately uncover novel biological insights. Support for multiple experimental conditions and time-series datasets, tools for generation of customization data, programmatic access, and a free user accounts system were introduced in this version to further streamline its workflow.
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发表时间: 2013-01
影响因子: 14.9
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