The genomic basis of evolutionary differentiation among honey bees.
The genomic basis of evolutionary differentiation among honey bees.
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DOI：
10.1101/gr.272310.120
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发表时间：
2021-07
期刊：
影响因子：
7
通讯作者：
Rueppell O
中科院分区：
文献类型：
--
作者：
Fouks B;Brand P;Nguyen HN;Herman J;Camara F;Ence D;Hagen DE;Hoff KJ;Nachweide S;Romoth L;Walden KKO;Guigo R;Stanke M;Narzisi G;Yandell M;Robertson HM;Koeniger N;Chantawannakul P;Schatz MC;Worley KC;Robinson GE;Elsik CG;Rueppell O
与西方蜜蜂（Apis mellifera）相比，其他蜜蜂物种尽管具有重要性和多样性，但在很大程度上被忽视了。蜜蜂进化多样化的遗传基础在很大程度上仍然未知。在这里，我们提供了三种蜜蜂物种的全基因组比较，每种蜜蜂代表蜜蜂的三个亚属之一，即侏儒蜜蜂（Apis florea），巨型蜜蜂（A. dorsata）和腔巢（A.意大利蜜蜂）蜜蜂与熊蜂作为外群。我们的分析解决了蜜蜂的繁殖问题，矮蜜蜂首先发散。我们发现，在蜜蜂的进化增加真社会的复杂性，通过增加基因调控的复杂性，这是与以前的研究一致。然而，这一过程似乎与转录控制以外的途径有关。蜜蜂的正选择模式揭示了维持基因组稳定性和产生遗传多样性之间的权衡，快速进化的皮尔纳途径导致基因组中的转座因子耗尽，以及快速进化的DNA修复途径与所有蜜蜂物种中的高重组率相关。蜜蜂内部的多样化伴随着几个基因的正选择，这些基因的假定功能为谱系特异性适应提供了候选机制，如迁移、免疫和筑巢行为。
In contrast to the western honey bee, Apis mellifera, other honey bee species have been largely neglected despite their importance and diversity. The genetic basis of the evolutionary diversification of honey bees remains largely unknown. Here, we provide a genome-wide comparison of three honey bee species, each representing one of the three subgenera of honey bees, namely the dwarf (Apis florea), giant (A. dorsata), and cavity-nesting (A. mellifera) honey bees with bumblebees as an outgroup. Our analyses resolve the phylogeny of honey bees with the dwarf honey bees diverging first. We find that evolution of increased eusocial complexity in Apis proceeds via increases in the complexity of gene regulation, which is in agreement with previous studies. However, this process seems to be related to pathways other than transcriptional control. Positive selection patterns across Apis reveal a trade-off between maintaining genome stability and generating genetic diversity, with a rapidly evolving piRNA pathway leading to genomes depleted of transposable elements, and a rapidly evolving DNA repair pathway associated with high recombination rates in all Apis species. Diversification within Apis is accompanied by positive selection in several genes whose putative functions present candidate mechanisms for lineage-specific adaptations, such as migration, immunity, and nesting behavior.
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影响因子：
4.8
作者：
DYER, FC;SEELEY, TD
通讯作者：
SEELEY, TD
影响因子：
10.7
作者：
Anisimova, Maria;Yang, Ziheng
通讯作者：
Yang, Ziheng
影响因子：
56.9
作者：
Delanoue, Renald;Meschi, Eleonora;Leopold, Pierre
通讯作者：
Leopold, Pierre
影响因子：
4.6
作者：
Chavez, Daniel E.;Gronau, Ilan;Wayne, Robert K.
通讯作者：
Wayne, Robert K.
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y