Psoriasis epidemiology screening tool (PEST) is useful for the detection of psoriatic arthritis in the Japanese population.
Psoriasis epidemiology screening tool (PEST) is useful for the detection of psoriatic arthritis in the Japanese population.
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银屑病流行病学筛查工具（PEST）可用于检测日本人群中的银屑病关节炎。
DOI：
10.1038/s41598-021-95620-4
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发表时间：
2021-08-09
影响因子：
4.6
通讯作者：
Nakamura M
中科院分区：
文献类型：
--
作者：
Setoyama A;Sawada Y;Saito-Sasaki N;Ohmori S;Omoto D;Yamamoto K;Yoshioka H;Okada E;Nakamura M
银屑病是一种慢性炎症性皮肤病，累及全身多个器官和组织，其特征是皮肤鳞状糜烂。在不同类型的银屑病中，银屑病关节炎（PsA）是经常报告的，并且偶尔发展成严重的关节炎，导致关节功能障碍。有各种工具，特别是问卷调查，以确定存在的PsA在欧洲和美国的人口，但是，鲜为人知的是，这些工具的效用在亚洲人口。在这项研究中，我们调查了一个有代表性的工具，银屑病流行病学筛查工具（PEST）问卷，以确定银屑病A的日本银屑病患者的效用。共有143例银屑病患者入组本研究。其中29例诊断为PsA。PEST评分> 3分者PsA检出率明显增高，敏感性为93.1%，特异性为78.9%。在PEST问卷中的问题中，“你有过关节肿胀吗？”PsA患者中回答“是”的频率最高。单因素和多因素分析显示，高PEST评分（> 3）是PsA患者的独立变量。总之，我们的研究表明，PEST问卷是一个有用的工具，以确定银屑病患者中的日本PsA。
Psoriasis is a chronic inflammatory skin disease that involves various systemic organs and tissues and is characterized by scaly erythematous skin. Among the different types of psoriasis, psoriatic arthritis (PsA) is frequently reported, and occasionally develops into severe arthritis leading to joint dysfunction. There are various tools, especially questionnaires, to identify the presence of PsA in European and American populations; however, little is known about the utility of these tools in the Asian population. In this study, we investigated the utility of a representative tool, the psoriasis epidemiology screening tool (PEST) questionnaire, to identify PsA among Japanese patients with psoriasis. A total of 143 patients with psoriasis were enrolled in this study. Among them, 29 patients were diagnosed with PsA. The frequency of PsA was significantly increased in patients with PEST scores > 3, with a sensitivity of 93.1% and a specificity of 78.9%. Among the questions in the PEST questionnaire, “Have you ever had a swollen joint?” showed the highest frequency to answer “Yes” among patients with PsA. Univariate and multivariate analyses revealed that high PEST scores (> 3) was an independent variable in PsA patients. Taken together, our study suggests that the PEST questionnaire is a useful tool to identify PsA among Japanese patients with psoriasis.
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DOI：
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发表时间：
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期刊：
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DOI：
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