Effects of baroceptor reflex on cardiac and renal sympathetic nerve activity before and after atropinization in awake cats at rest.
Effects of baroceptor reflex on cardiac and renal sympathetic nerve activity before and after atropinization in awake cats at rest.
复制标题
清醒猫休息时阿托品化前后压力感受器反射对心脏和肾交感神经活动的影响。
DOI：
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Aklhlro Nabuchi
中科院分区：
文献类型：
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作者：
I. Ninomiya;K. Matsukawa;T. Honda;N. Nishiura;Aklhlro Nabuchi
在阿托品（0.1mg/kg，i. v.）有意识的猫休息时的状态。MCSNA、mRNA、平均主动脉压（MAP）和心率（HR）的静息值分别为85 +/- 6 imps/s、76 +/- 11 imps/s、100 +/- 4 mmHg和164 +/- 10次/min。在90-140 mmHg范围内，MCSNA和mRNA的变化几乎与绝对MAP的变化成反比。在此压力范围内，压力感受器-交感神经系统对心脏和肾脏的增益分别为2.31和1.84。MCSNA以及mRNA分别在MAP为142和150 mmHg时降低至噪声水平。用阿托品，MCSNA和mRNA被中枢抑制，而HR增加至192次/分钟。阿托品可使血压从对照组的31 ± 4 mmHg升高到75 ± 7 mmHg。MAP-MCSNA和MAP-mRNA的分段线性关系变为显著的顺时针滞后环。在MAP上升期间，压力感受器-交感神经系统的增益在MCSNA和mRNA中分别下降到0.91和0.97。在返回MAP期间，MCSNA和mRNA的延迟激活集中发生。我们的结论是，MCSNA的压力感受器反射的影响是大于对mRNA，和MCSNA和mRNA的压力感受器控制修改中央阿托品在清醒的猫休息。
The effects of baroceptor reflex on mean cardiac (MCSNA) and renal sympathetic nerve activity (MRNA) were analyzed before and after atropinized (0.1 mg/kg, i.v.) states in conscious cats at rest. Resting values of MCSNA, MRNA, mean aortic pressure (MAP), and heart rate (HR) were 85 +/- 6 imps/s, 76 +/- 11 imps/s, 100 +/- 4 mmHg, and 164 +/- 10 beats/min, respectively. Both MCSNA and MRNA changed almost inversely to changes in the absolute MAP in the range of 90-140 mmHg. Within this pressure range the gain of baroceptor-sympathetic system to the heart and kidney was 2.31 and 1.84, respectively. MCSNA as well as MRNA was reduced to the noise level at the MAP of 142 and 150 mmHg, respectively. With atropine, MCSNA and MRNA were inhibited centrally whereas HR increased to 192 beats/min. The increase in MAP caused by norepinephrine (2.1 micrograms/kg, i.v.) was enhanced to 75 +/- 7 mmHg by atropine from 31 +/- 4 mmHg in control. The piecewise linear MAP-MCSNA and MAP-MRNA relationships changed to a remarkable clockwise hysteresis loop. During the rising MAP period, the gain of the baroceptor-sympathetic system decreased to 0.91 and 0.97 in MCSNA and MRNA, respectively. During the returning MAP period, a delayed activation in MCSNA and MRNA occurred centrally. We conclude that the baroceptor reflex effect on MCSNA is larger than those on MRNA, and that the baroceptor control of MCSNA and MRNA is modified centrally by atropine in the awake cat at rest.
扩容对清醒犬肾神经活动、肾血流量以及钠和水排泄的影响。
DOI：
10.1152/ajprenal.1985.249.5.f680
发表时间：
1985
期刊：
The American journal of physiology
影响因子：
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作者：
Morita,H;Vatner,SF
通讯作者：
Vatner,SF
清醒兔子压力升高后压力反射对交感神经活动的控制。
DOI：
10.1152/ajpheart.1985.248.6.h827
发表时间：
1985
期刊：
The American journal of physiology
影响因子：
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作者：
Undesser,KP;Pan,JY;Lynn,MP;Bishop,VS
通讯作者：
Bishop,VS