Light-intensity physical activity and cardiometabolic biomarkers in US adolescents.
Light-intensity physical activity and cardiometabolic biomarkers in US adolescents.
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DOI：
10.1371/journal.pone.0071417
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Salmon J
中科院分区：
文献类型：
--
作者：
Carson V;Ridgers ND;Howard BJ;Winkler EA;Healy GN;Owen N;Dunstan DW;Salmon J
对青少年有益的最低体力活动强度尚不清楚。本研究的目的是在大样本人群中检查加速度计产生的光强度（分为低强度和高强度）体力活动以及中等强度至剧烈强度体力活动与心脏代谢生物标志物的相关性。该研究基于2003/04和2005/06年国家健康和营养调查中的1，731名12-19岁青少年。低光强度活动（100-799计数/分钟）、高光强度活动（800计数/分钟至<4 MET）和中等强度至剧烈强度活动（≥4 MET，Freedson年龄特异性方程）由加速度计得出。测量心脏代谢生物标志物，包括腰围、收缩压、舒张压、HDL-胆固醇和C-反应蛋白。还在空腹子样本（n = 807）中测量甘油三酯、LDL-胆固醇、胰岛素、葡萄糖和β细胞功能（HOMA-%B）和胰岛素敏感性（HOMA-%S）的稳态模型评估。 调整混杂因素后，每天每增加1小时的低强度活动与舒张压降低0.59（95%CI：1.18-0.01）mmHG相关。每增加一小时/天的高光强度活动与舒张压降低1.67（2.94-0.39）mmHG和HDL-胆固醇升高0.04（0.001-0.07）mmol/L相关。每天每增加1小时的中强度至高强度活动，收缩压降低3.54（5.73-1.35）mmHG，腰围降低5.49（1.11-9.77）%，胰岛素降低25.87（6.08-49.34）%，HOMA-%S升高16.18（4.92-28.53）%。在低光强度体力活动和高光强度体力活动中花费的时间与生物标志物有一些有利的关联。与目前对青少年的体力活动建议一致，中度至剧烈强度的活动与许多心脏代谢生物标志物有良好的相关性。虽然增加MVPA仍然应该是公共卫生的优先事项，但需要进一步研究以确定光强度活动阈值的剂量-反应关系，以告知未来的青少年建议和干预措施。
The minimal physical activity intensity that would confer health benefits among adolescents is unknown. The purpose of this study was to examine the associations of accelerometer-derived light-intensity (split into low and high) physical activity, and moderate- to vigorous-intensity physical activity with cardiometabolic biomarkers in a large population-based sample. The study is based on 1,731 adolescents, aged 12–19 years from the 2003/04 and 2005/06 National Health and Nutrition Examination Survey. Low light-intensity activity (100–799 counts/min), high light-intensity activity (800 counts/min to <4 METs) and moderate- to vigorous-intensity activity (≥4 METs, Freedson age-specific equation) were accelerometer-derived. Cardiometabolic biomarkers, including waist circumference, systolic blood pressure, diastolic blood pressure, HDL-cholesterol, and C-reactive protein were measured. Triglycerides, LDL- cholesterol, insulin, glucose, and homeostatic model assessments of β-cell function (HOMA-%B) and insulin sensitivity (HOMA-%S) were also measured in a fasting sub-sample (n = 807). Adjusted for confounders, each additional hour/day of low light-intensity activity was associated with 0.59 (95% CI: 1.18–0.01) mmHG lower diastolic blood pressure. Each additional hour/day of high light-intensity activity was associated with 1.67 (2.94–0.39) mmHG lower diastolic blood pressure and 0.04 (0.001–0.07) mmol/L higher HDL-cholesterol. Each additional hour/day of moderate- to vigorous-intensity activity was associated with 3.54 (5.73–1.35) mmHG lower systolic blood pressure, 5.49 (1.11–9.77)% lower waist circumference, 25.87 (6.08–49.34)% lower insulin, and 16.18 (4.92–28.53)% higher HOMA-%S. Time spent in low light-intensity physical activity and high light-intensity physical activity had some favorable associations with biomarkers. Consistent with current physical activity recommendations for adolescents, moderate- to vigorous-intensity activity had favorable associations with many cardiometabolic biomarkers. While increasing MVPA should still be a public health priority, further studies are needed to identify dose-response relationships for light-intensity activity thresholds to inform future recommendations and interventions for adolescents.
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影响因子：
120.7
作者：
Ekelund, Ulf;Luan, Jian'an;Sherar, Lauren B.;Esliger, Dale W.;Griew, Pippa;Cooper, Ashley
通讯作者：
Cooper, Ashley
DOI：
10.1186/1479-5868-5-45
发表时间：
2008-09-10
影响因子：
8.7
作者：
Ridley, Kate;Ainsworth, Barbara E.;Olds, Tim S.
通讯作者：
Olds, Tim S.
DOI：
10.1186/1479-5868-9-15
发表时间：
2012-02-19
期刊：
The international journal of behavioral nutrition and physical activity
影响因子：
--
作者：
Ridgers ND;Salmon J;Ridley K;O'Connell E;Arundell L;Timperio A
通讯作者：
Timperio A
影响因子：
7.1
作者：
Gutin, B;Yin, ZO;Barbeau, P
通讯作者：
Barbeau, P
DOI：
10.1249/01.mss.0000185674.09066.8a
发表时间：
2005-11-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
M창sse, LC;Fuemmeler, BF;Treuth, M
通讯作者：
Treuth, M