Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma.
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma.
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DOI：
10.1016/j.mito.2022.11.001
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发表时间：
2023-01
期刊：
影响因子：
4.4
通讯作者：
Rabchevsky, Alexander G.
中科院分区：
文献类型：
--
作者：
Patel, Samir P.;Michael, Felicia M.;Gollihue, Jenna L.;Hubbard, W. Brad;Sullivan, Patrick G.;Rabchevsky, Alexander G.
Herein, we review evidence that targeting mitochondrial dysfunction with ‘mitoceuticals’ is an effective neuroprotective strategy following neurotrauma, and that isolated exogenous mitochondria can be effectively transplanted into host spinal cord parenchyma to increase overall cellular metabolism. We further discuss control measures to ensure greatest potential for mitochondrial transfer, notably using erodible thermogelling hydrogels to deliver respiratory competent mitochondria to the injured spinal cord.
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影响因子：
64.5
作者：
KING, MP;ATTARDI, G
通讯作者：
ATTARDI, G
DOI：
10.1152/ajpheart.00567.2008
发表时间：
2009-01-01
影响因子：
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作者：
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作者：
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Rabchevsky, Alexander G.
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Caicedo, Andres
影响因子：
4.4
作者：
Gollihue JL;Rabchevsky AG
通讯作者：
Rabchevsky AG