Trends in colorectal cancer mortality in hispanics: a SEER analysis.
Trends in colorectal cancer mortality in hispanics: a SEER analysis.
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DOI：
10.18632/oncotarget.21938
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发表时间：
2017-12-12
期刊：
影响因子：
--
通讯作者：
Lenz HJ
中科院分区：
文献类型：
--
作者：
Barzi A;Yang D;Mostofizadeh S;Lenz HJ
西班牙裔结直肠癌（CRC）死亡率低于非西班牙裔白人（NHW）。如果拉美裔人得到公平的照顾，并实现同样程度的健康效益，他们的生存率更高的趋势应该保持。这项研究评估了西班牙裔随时间推移的死亡率趋势，以比较他们与NHW的生存改善。我们使用了监测、流行病学和最终结果计划（SEER）的基于发病率的死亡率数据库来评估死亡率差距，死亡率差距定义为NHWs和西班牙裔美国人之间特定阶段死亡率的差异，目前西班牙裔美国人具有优势。不同种族的CRC分期特异性死亡率存在统计学显著差异，西班牙裔转移性疾病死亡比例高于NHW（分别为48%和44%）。比较2000-2005年和2006-2011年的时间间隔，新保健工作者的死亡率下降了15.1%，西班牙裔下降了5.9%，从而缩小了死亡率差距。西班牙裔和NHW之间的死亡率差距随着疾病的每个阶段逐渐缩小，反映出西班牙裔在CRC死亡率方面存在差异。西班牙裔和NHWs之间的死亡率差距正在缩小，支持西班牙裔的死亡率改善率显着降低。如果目前的趋势继续下去，西班牙裔的死亡率将超过非卫生工作者。
Colorectal cancer (CRC) mortality among Hispanics is lower than Non-Hispanic Whites (NHW). If Hispanics receive equitable care and achieve the same degree of health benefit, their trend of better survival should be maintained. This study assesses mortality trends among Hispanics overtime to compare their survival improvement with NHW. We used the Incidence-Based Mortality database of the Surveillance, Epidemiology, and End Results Program (SEER) to assess the mortality gap, which is defined as the difference in stage-specific mortality between NHWs and Hispanics, and currently has an advantage for Hispanics. There is a statistically significant disparity in stage-specific mortality of CRC by race, with a higher proportion of deaths from metastatic disease among Hispanics than NHW (48% vs. 44% respectively). Comparing the time intervals of 2000-2005 and 2006-2011, mortality was reduced by 15.1% for NHWs and 5.9% for Hispanics, resulting in a narrowing of the mortality gap. The mortality gap between Hispanics and NHW is tapering overtime for every stage of the disease, reflecting that Hispanics have a disparity in CRC mortality. The mortality gap between Hispanics and NHWs is narrowing, supporting a significantly lower rate of mortality improvement in Hispanics. If the current trend continues, mortality rates in Hispanics will outpace that of NHWs.
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