Drosophila conditioned courtship: two ways of testing memory.
Drosophila conditioned courtship: two ways of testing memory.
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果蝇条件求爱：测试记忆的两种方法。
DOI：
10.1101/lm.6.1.1
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发表时间：
1999
影响因子：
2
通讯作者：
J. Bragina
中科院分区：
文献类型：
--
作者：
N. Kamyshev;K. Iliadi;J. Bragina
在果蝇中，有过求偶经历的雄性果蝇的求偶行为减少是因为一种有吸引力的无条件刺激(US)--壮阳药--的抵消作用，这种刺激在与令人厌恶的美国--抗性药--配对后，变成了一种厌恶的条件性刺激(CS)。在对缺乏抗雌雄药的处女进行的保持测试中，雄性在训练后3小时内保持较低水平的求爱。然而，一项衡量求爱抑制的指标--学习指数(LI)仅在1小时后显著下降。相比之下，在与交配的雌性动物的再训练测试中，LI在训练后8小时没有下降，但在训练16小时后降至显著水平。这些结果从培训转移的角度进行了讨论。非特异性迁移和非关联性行为改变在训练迁移中的作用很小。再培训测验被推荐为研究条件恋爱的一种新方法。根据这里提出的模型，在对处女的测试中，记忆保持的持续时间受到CS和厌恶动机系统之间的直接联系的保持或美国内部表征的保持的限制。在再培训测试中，CS-US协会似乎是唯一参与培训后3小时或更长时间转会的因素。
In Drosophila, courtship reduction in male flies that have previous experience of courting a mated female is a result of the counterconditioning of an attractive unconditioned stimulus (US)--the aphrodisiac--which becomes an aversive conditioned stimulus (CS) after being paired with an aversive US--the antiaphrodisiac. In a retention test with a virgin female lacking the antiaphrodisiac, males retain a lower level of courtship for 3 hr after training. However, a measure of courtship suppression, the learning index (LI), decreases significantly after only 1 hr. In contrast, in the retraining test with a mated female, the LI shows no decrease for 8 hr but falls below significance 16 hr after training. These results are discussed in terms of the transfer of training. Nonspecific transfer and nonassociative behavioral modifications play little, if any, role in the transfer of training. The retraining test is recommended as a new protocol for studying conditioned courtship. According to the model proposed here, in tests with a virgin female, the duration of memory retention is limited by the retention of the direct association between the CS and the aversive motivational system or by the retention of an internal representation of the US. In retraining tests, the CS-US association seems to be the only factor involved in transfer 3 or more hours after training.
果蝇暗色行板节律突变体的条件求偶分析。
DOI：
10.1101/lm.2.2.49
发表时间：
1995
期刊：
Learning & memory (Cold Spring Harbor, N.Y.)
影响因子：
--
作者：
vanSwinderen,B;Hall,JC
通讯作者：
Hall,JC