Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes.
Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes.
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DOI：
10.1111/j.1399-5448.2011.00837.x
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发表时间：
2012-06
影响因子：
3.4
通讯作者：
Diabetes Research in Children Network Study Group
中科院分区：
文献类型：
--
作者：
Tsalikian E;Fox L;Weinzimer S;Buckingham B;White NH;Beck R;Kollman C;Xing D;Ruedy K;Diabetes Research in Children Network Study Group
探讨连续血糖监测 (CGM) 在患有 1 型糖尿病 (T1D) 的幼儿中使用的可行性。为 23 名 4 岁以下患有 T1D 的儿童提供了 FreeStyle Navigator® (n=21) 或 Paradigm® (n=2) CGM 设备。基线时，平均年龄为 3.0 ± 0.8 岁，平均 HbA1c 为 8.0 ± 0.8%，10 名患者使用胰岛素泵，13 名患者每日多次注射。对 CGM 的使用进行了为期 6 个月的评估。三名儿童在 6 个月结束前退出研究。在完成 6 个月随访的 20 名儿童中，第 6 个月的连续血糖监测使用时间≥6 天/周的有 9 名（45%），4-<6 天/周的 2 名（10%），以及 <4 天/周的 9 名（45%）。皮肤反应极小。尽管基线和 6 个月之间的平均 HbA1c 没有可检测到的变化（分别为 7.9% 和 8.0%），但根据 CGM 满意度量表问卷的测量，家长对 CGM 的满意度很高。大部分血糖值处于高血糖范围内，生化低血糖并不常见。超过 40% 的幼儿能够在 6 个月后几乎每天安全地使用 CGM。 CGM 表现出频繁的高血糖波动，血糖读数变化很大。尽管整个组的血糖控制没有改善，但家长对 CGM 的满意度很高。
To examine the feasibility of continuous glucose monitoring (CGM) use in very young children with type 1 diabetes (T1D). 23 children less than 4 years of age with T1D were provided with a FreeStyle Navigator® (n=21) or a Paradigm® (n=2) CGM device. At baseline, mean age was 3.0 ± 0.8 years, mean HbA1c was 8.0 ± 0.8 %, 10 were using an insulin pump and 13 were on multiple daily injections. CGM use was evaluated over a 6-month period. Three children dropped out of the study before the end of 6 months. Among the 20 children who completed 6 months of follow-up, CGM use in month 6 was ≥6 days/week in 9 (45%), 4-<6 days/week in 2 (10%), and <4 days/week in 9 (45%). Skin reactions were minimal. Although there was no detectable change in mean HbA1c between baseline and 6 months (7.9% and 8.0%, respectively), there was a high degree of parental satisfaction with CGM as measured on the CGM Satisfaction Scale questionnaire. A high percentage of glucose values were in the hyperglycemic range and biochemical hypoglycemia was infrequent. More than 40% of very young children were able to safely use CGM on a near daily basis after 6 months. CGM demonstrated frequent hyperglycemic excursions, with a large variability in glucose readings. Although improvement in glycemic control was not detected in the group as a whole, parental satisfaction with CGM was high.
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影响因子：
5.1
作者：
DiMeglio, LA;Pottorff, TM;Eugster, EA
通讯作者：
Eugster, EA
影响因子：
16.2
作者：
Beck, Roy W.
通讯作者：
Beck, Roy W.
影响因子：
1.6
作者：
HAUMONT, D;DORCHY, H;PELC, S
通讯作者：
PELC, S
影响因子：
8
作者：
Weinzimer, SA;Ahern, JH;Tamborlane, WV
通讯作者：
Tamborlane, WV
影响因子：
5.4
作者：
Gandrud, Laura M.;Xing, Dongyuan;Buckingham, Bruce A.
通讯作者：
Buckingham, Bruce A.