Monte Carlo modeling of the transverse-axis dose distribution of the model 200 103Pd interstitial brachytherapy source.

Monte Carlo modeling of the transverse-axis dose distribution of the model 200 103Pd interstitial brachytherapy source.
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对模型 200 103Pd 间质近距离放射治疗源的横轴剂量分布进行蒙特卡罗建模。

DOI:
10.1118/1.598924
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发表时间:
2000
期刊:
影响因子:
3.8
通讯作者:
Williamson,JF
Williamson,JF
中科院分区:
医学3区
文献类型:
--
作者:
Williamson,JF

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本研究首次对200型组织间近距离放射治疗源的绝对剂量率分布进行了理论分析。蒙特卡罗光子输运(MCPT)模拟技术已被用于评估200型源的横轴剂量率分布,该分布是Pd金属涂层厚度的函数(包括镀在种子内包含的直圆柱形石墨颗粒表面上的Pd金属涂层)。通过模拟广角自由空气室(WAFAC)校准几何结构,实际估计了剂量率常数Λ。WAFAC是NIST(美国国家标准与技术研究所)最近实施的空气比释动能强度主要标准的实验实现。我们的结果表明,极角和距离相关的斜向过滤和屏蔽效应在横轴附近引起显著和意外的光子通量各向异性,并在典型的校准距离处引起平方反比律偏差。任何放射源,只要放射性沉积在具有锐边的高衰减表面上,都可能表现出这种效应。对于200型种子,钯金属厚度不会显着影响水中距离小于5厘米的相对剂量分布,但确实使Λ对测量几何形状敏感。幸运的是,WAFAC在足够大的孔径上平均了通量,得到的Λ为0.68±0.02 cGy <$h−1 <$U−1,几乎与Pd金属层厚度无关,与最近的测量和计算非常一致。这个值比重正化任务组43的Λ值高20%。
This study presents the first theoretical analysis of the absolute dose‐rate distribution about the Model 200 interstitial brachytherapy source. Monte Carlo photon‐transport (MCPT) simulation techniques have been used to evaluate the transverse‐axis dose‐rate distribution of the Model 200 source as a function of thickness of the Pd metal coating (containing the plated onto the surfaces of right cylindrical graphite pellets contained within the seed. The dose‐rate constant, Λ, was realistically estimated by simulating the wide‐angle, free‐air chamber (WAFAC) calibration geometry. The WAFAC is the experimental realization of NIST's (National Institute of Standards and Technology) recently implemented primary standard of air‐kerma strength Our results show that polar angle‐ and distance‐dependent oblique filtration and shielding effects induce significant and unexpected photon fluence anisotropy near the transverse‐axis and inverse square law deviations at typical calibration distances. Any source consisting of radioactivity deposited on a highly attenuating surface with sharp edges may exhibit such effects. In the case of the Model 200 seed, the Pd metal thickness does not significantly influence the relative dose distribution in water at distances less than 5 cm, but does make Λ sensitive to the measurement geometry. Fortunately, the WAFAC averages fluence over a sufficiently large aperture that the resultant Λ, 0.68±0.02 cGy⋅h−1⋅U−1, is almost independent of Pd metal layer thickness and in close agreement with recent measurements and calculations. This value is 20% higher than that of the renormalized Task Group 43 Λ value.
用于辐射传输计算的基于体积的几何建模。
DOI: 10.1118/1.596810
发表时间: 1992
期刊: Medical physics
影响因子: 3.8
作者:
Li,Z;Williamson,JF
通讯作者: Williamson,JF
103Pd 近距离放射治疗剂量处方。
DOI: --
发表时间: 1999
期刊: Medical Physics (Lancaster)
影响因子: --
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通讯作者: R. Wallace
DOI: --
发表时间: 1998
期刊: Medical Physics (Lancaster)
影响因子: --
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125I 和 103Pd 源的各向异性函数。
DOI: --
发表时间: 1998
期刊: Medical Physics (Lancaster)
影响因子: --
作者:
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用于脉冲剂量率近距离放射治疗的高强度 Ir-192 源的蒙特卡罗剂量计算的实验验证。
DOI: 10.1118/1.597484
发表时间: 1995
期刊: Medical physics
影响因子: 3.8
作者:
Valicenti,RK;Kirov,AS;Meigooni,AS;Mishra,V;Das,RK;Williamson,JF
通讯作者: Williamson,JF