Decrease in peak heart rate with acute hypoxia in relation to sea level V̇O2max
Decrease in peak heart rate with acute hypoxia in relation to sea level V̇O2max
复制标题
急性缺氧时峰值心率降低与海平面 V̇O2max 的关系
DOI：
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发表时间：
2003
影响因子：
3
通讯作者：
C. Denis
中科院分区：
文献类型：
--
作者：
H. Benoit;T. Busso;J. Castells;A. Geyssant;C. Denis
本研究的目的是评估动脉血氧饱和度（SaO 2）的影响，在最大的运动在急性缺氧条件下与常氧相比，最大心率。根据海平面最大耗氧量（V ~ O2 max）将46名雄性动物分为3组：高组[GH，V ~ O2 max =64.2（3.3）ml.min-1.kg-1]、中组[GM，50.8（3.9）ml.min-1.kg-1]和低组[GL，41.0（1.9）ml.min-1.kg-1]。所有受试者在两种吸入氧分压（PIO 2，149 mmHg和70 mmHg）条件下进行最大运动试验。在GM组中，7名受试者在PIO 2 136、118、104、92和80 mmHg下进行了5次补充递增运动试验。在所有PIO 2水平下，使用耳氧计测量VtoO 2 max和SaO 2。PIO 2使SaO 2和峰值心率（HRpeak）从104和92 mmHg显著降低。SaO 2与HR峰值下降相关。当PIO 2 =70 mmHg时，GH的V ~ O2 max、SaO 2和HR峰值分别下降44%、62%和17.0 bpm，GM下降38%、68%和14.7 bpm，GL下降34%、68%和11.8 bpm。低氧极量运动时，GH组SaO_2低于GM和GL组（P<0.01）。在GH组受试者中，5例在常氧条件下运动时出现运动性低氧血症（EIH）。在最大低氧运动时，EIH组的HR峰值下降幅度大于非EIH组（21.2 bpm vs. 15.0 bpm; p<0.05）。当受试者暴露于急性缺氧时，较低的SaO 2（由于较低的PIO 2或训练状态）与较低的HRpeak相关。
The aim of this study was to evaluate the influence of arterial oxygen saturation (SaO2) on maximal heart rate during maximal exercise under conditions of acute hypoxia compared with normoxia. Forty-six males were divided into three groups depending on their sea level maximal oxygen consumption (V̇O2max): high [GH, V̇O2max=64.2 (3.3) ml.min−1.kg−1], medium [GM, 50.8 (3.9) ml.min−1.kg−1] and low [GL, 41.0 (1.9) ml.min−1.kg−1]. All subjects performed a maximal exercise test in two conditions of inspired oxygen tension (PIO2, (149 mmHg and 70 mmHg). Among the GM group, seven subjects performed five supplementary incremental exercise tests at PIO2 136, 118, 104, 92, and 80 mmHg. Measurements of V̇O2max and SaO2 using an ear-oxymeter were carried out at all levels of PIO2. The decrease in SaO2 and peak heart rate (HRpeak) with PIO2 became significant from 104 and 92 mmHg. SaO2 correlated with the decrease in HRpeak. For PIO2=70 mmHg, the decrease in V̇O2max, SaO2 and HRpeak was, respectively, 44%, 62%, and 17.0 bpm for GH, 38%, 68%, and 14.7 bpm for GM, and 34%, 68%, and 11.8 bpm for GL. During maximal exercise in hypoxia, SaO2 was lower for GH than GM and GL (p<0.01). Among subjects in GH, five presented exercise-induced hypoxemia (EIH) when exercising in normoxia. The EIH group exhibited a greater decrement in HRpeak than the non-EIH group at maximal hypoxic exercise (21.2 bpm vs. 15.0 bpm; p<0.05). When subjects are exposed to acute hypoxia, the lower SaO2, due either to lower PIO2 or to training status, is associated with lower HRpeak.
不完全肺气体交换对最大摄氧量的影响。
DOI：
10.1152/jappl.1989.66.6.2491
发表时间：
1989
期刊：
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子：
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作者：
Powers,SK;Lawler,J;Dempsey,JA;Dodd,S;Landry,G
通讯作者：
Landry,G
高原最大心输出量降低——机制和意义。
DOI：
10.1016/s0034-5687(99)00101-2
发表时间：
2000
期刊：
Respiration physiology
影响因子：
--
作者：
Wagner,PD
通讯作者：
Wagner,PD