Juvenile hormone action to suppress gene transcription and influence message stability.
Juvenile hormone action to suppress gene transcription and influence message stability.
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保幼激素抑制基因转录并影响信息稳定性的作用。
DOI:
10.1002/dvg.1020140410
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发表时间:
1993
期刊:
影响因子:
--
通讯作者:
Schelling,D
中科院分区:
文献类型:
--
作者:
Jones,G;Venkataraman,V;Manczak,M;Schelling,D
Proteins normally expressed in high abundance only at larval‐pupal metamorphosis inTrichoplusia niwere examined in a comparative analysis of the role and level of hormonal control of their expression. Some related proteins in the hemocyanin‐superfamily (i.e., an acidic protein [AJHSP1] and two basic proteins [BJHSP1, BJHSP2]) were shown by nuclear run‐on analysis to be specifically transcriptionally suppressed by juvenile hormone (JH), while transcription of another member of that family which is also metamorphosis‐associated (arylphorin) was not specifically sensitive to JH. The stability of the mRNA for those members transcriptionally down‐regulated by JH appeared to decrease under high JH conditions. While each protein was resorbed to some extent by the prepupal fat body, only the two basic proteins were quantitatively cleared from prepupal hemolymph. The JH‐sensitive proteins studied appear to be encoded in single copy genes not immediately juxtaposed in the genome. These and previous studies now permit a more comprehensive understanding of the different combinations of mechanisms involving transcription, mRNA stability, translation, and protein clearance that operate to regulate these metamorphosis‐associated proteins. © 1993Wiley‐Liss, Inc.
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影响因子:
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作者:
C. Weldon Jones;F. C. Kafatos
通讯作者:
F. C. Kafatos
DOI:
--
发表时间:
1987
期刊:
影响因子:
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作者:
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作者:
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通讯作者:
G. R. Wyatt
DOI:
--
发表时间:
1991
期刊:
影响因子:
--
作者:
S. R. Palli;S. Mcclelland;K. Hiruma;B. Latli;L. Riddiford
通讯作者:
L. Riddiford