Early sexual maturation, central adiposity and subsequent overweight in late adolescence. a four-year follow-up of 1605 adolescent Norwegian boys and girls: the Young HUNT study.
Early sexual maturation, central adiposity and subsequent overweight in late adolescence. a four-year follow-up of 1605 adolescent Norwegian boys and girls: the Young HUNT study.
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性成熟提前、中心性肥胖以及随后的青春期后期超重。对 1605 名挪威青少年男孩和女孩进行为期四年的跟踪调查：Young HUNT 研究。
DOI：
10.1186/1471-2458-7-54
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发表时间：
2007-04-12
影响因子：
4.5
通讯作者：
Vatten LJ
中科院分区：
文献类型：
--
作者：
Bratberg GH;Nilsen TI;Holmen TL;Vatten LJ
性成熟过早与超重有关，超重可能在生物生长和发育完成后持续存在。我们前瞻性地研究了早期性成熟对青春期后期超重的影响，并评估了这种关联是否会因青春期早期的中枢性肥胖而改变。对 1605 名挪威青少年进行了从早期（基线，平均年龄 14.2 岁）到青春期晚期（随访，平均年龄 18.2 岁）的随访。成熟时间是通过男孩的青春期状态（PDS）和女孩的初潮年龄（AAM）的自我报告来评估的。根据基线测量的腰围（腰围）对中心性肥胖进行分类，并使用年龄和性别特定的中位数作为截止值。根据国际肥胖工作组 (IOTF) 标准对超重进行分类。在随访中，女孩性成熟过早与超重有关，而男孩则不然。然而，这种关联仅限于基线时腰围较高（>中值）的女孩（OR，2.7，95% CI 1.5-4.9）。因此，对于基线时腰围较低（≤中位数）的女孩来说，初潮年龄与超重无关。与成熟时间无关，中心性肥胖与两性随访时较高的 BMI 相关，但早熟女孩 (3.5 kg/m2) 的差异比中熟女孩 (2.7 kg/m2) 和晚熟女孩 (1.2 kg/m2) 更明显。对于女孩来说，中心性肥胖和月经初潮过早的结合似乎会增加青春期后期超重的风险。
Early sexual maturation has been associated with overweight that may persist after the completion of biological growth and development. We have prospectively examined the influence of early sexual maturation on subsequent overweight in late adolescence and assessed if this association was modified by central adiposity in early adolescence. 1605 Norwegian adolescents were followed from early (baseline, mean age 14.2 years) to late adolescence (follow-up, mean age 18.2 years). Maturational timing was assessed by self-reports of pubertal status (PDS) in boys and age at menarche (AAM) in girls. Central adiposity was classified according to waist circumference (waist) measured at baseline, using age and gender specific medians as cut off. Overweight was classified according to International Obesity Task Force (IOTF) standards. At follow-up, early sexual maturation in girls, but not in boys, was associated with overweight. This association, however, was restricted to girls with high waist circumference (> median) at baseline (OR, 2.7, 95% CI 1.5–4.9). Thus, age at menarche was not associated with overweight in girls with low waist (≤ median) at baseline. Central adiposity was, independent of maturational timing, associated with higher BMI at follow-up in both genders, but differences were more pronounced among early matured girls (3.5 kg/m2), than among intermediate (2.7 kg/m2) and late matured girls (1.2 kg/m2). In girls, the combination of central adiposity and early age at menarche appears to increase the risk of being overweight in late adolescence.
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影响因子：
4.9
作者：
Goran, MI;Gower, BA;Nagy, TR
通讯作者：
Nagy, TR
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7.2
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5
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作者：
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