Eating disorder behaviours amongst adolescents: investigating classification, persistence and prospective associations with adverse outcomes using latent class models.

Eating disorder behaviours amongst adolescents: investigating classification, persistence and prospective associations with adverse outcomes using latent class models.
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DOI:
10.1007/s00787-016-0877-7
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发表时间:
2017-02
影响因子:
6.4
通讯作者:
Field, A. E.
Field, A. E.
中科院分区:
医学2区
文献类型:
--
作者:
Micali, Nadia;Horton, N. J.;Crosby, R. D.;Swanson, S. A.;Sonneville, K. R.;Solmi, F.;Calzo, J. P.;Eddy, K. T.;Field, A. E.

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进食障碍(艾德)的诊断标准仍然主要基于临床表现,但并没有涵盖人群中的全部行为。我们的目的是推导出一个经验为基础的艾德行为分类,在青春期的三个时间点使用行为和身体质量指数(BMI)指标,并验证类调查与不良后果的前瞻性关联。来自雅芳父母和孩子纵向研究(ALSPAC)的青少年提供了14岁(n = 6615)、16岁(n = 5888)和18岁(n = 5100)时的艾德数据,并测量了体重和身高。在15.5/16岁和17.5/18岁时评估心理和行为结局。我们拟合了性别和年龄分层的潜在类模型,并采用逻辑回归来研究类与后来的结果之间的关联。在每个时间点观察到一个无症状和两个有症状(主要代表较高和较低频率的艾德行为)类别,尽管其相对患病率因年龄和性别而异。在随后的评估中,有症状班级的大多数女孩仍然有症状。症状类的女孩有较高的几率随后焦虑和抑郁症,酗酒,吸毒,故意自残。男孩的数据分析能力不足。存在两种症状类别(以不同的艾德行为频率为特征)及其与不良结局的前瞻性相关性,表明需要根据经验数据完善诊断阈值。尽管班级有一些不稳定性,特别是在青春期中期,但有证据表明,有症状的班级中有一半的女孩仍然有症状,这表明青春期艾德行为的持续存在,并强调了早期识别以减少慢性化的必要性。
Diagnostic criteria for eating disorders (ED) remain largely based on clinical presentations, but do not capture the full range of behaviours in the population. We aimed to derive an empirically based ED behaviour classification using behavioural and body mass index (BMI) indicators at three time-points in adolescence, and to validate classes investigating prospective associations with adverse outcomes. Adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) provided data on ED at age 14 (n = 6615), 16 (n = 5888), and 18 years (n = 5100), and had weight and height measured. Psychological and behavioural outcomes were assessed at 15.5/16 and 17.5/18 years. We fit gender- and age-stratified latent class models, and employed logistic regression to investigate associations between classes and later outcomes. One asymptomatic and two symptomatic (largely representing higher and lower frequency ED behaviours) classes were observed at each time-point, although their relative prevalence varied by age and gender. The majority of girls in symptomatic classes remained symptomatic at subsequent assessments. Girls in symptomatic classes had higher odds of subsequent anxiety and depressive disorders, binge drinking, drug use, and deliberate self-harm. Data analyses were underpowered amongst boys. The presence of two symptomatic classes (characterised by different ED behaviour frequency) and their prospective association with adverse outcomes suggest a need to refine diagnostic thresholds based on empirical data. Despite some instability of classes, particularly in mid-adolescence, evidence that half of girls in symptomatic classes remained symptomatic suggests persistence of ED behaviours in adolescence, and highlights a need for early identification to reduce chronicity.
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