The effect of iron depletion on chronic hepatitis C virus infection.
The effect of iron depletion on chronic hepatitis C virus infection.
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DOI:
10.1007/s12072-008-9076-z
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发表时间:
2008-09
影响因子:
6.6
通讯作者:
Lippi, Giuseppe
中科院分区:
文献类型:
--
作者:
Franchini, Massimo;Targher, Giovanni;Capra, Franco;Montagnana, Martina;Lippi, Giuseppe
Increasing evidence exists that iron overload, a common finding in chronic hepatitis C virus (HCV) infection, plays an important role in the pathophysiology of this disease. The mechanisms by which iron excess induces liver damage along with the benefit of iron depletion via phlebotomy on biochemical and histological outcomes in patients with chronic HCV infection have been discussed in this review. Finally, we focus on the effect of iron reduction on the rate of response to interferon antiviral therapy.
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