Stepped care for obsessive-compulsive disorder: An open trial.
Stepped care for obsessive-compulsive disorder: An open trial.
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DOI：
10.1016/j.brat.2010.07.010
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发表时间：
2010-11
影响因子：
4.1
通讯作者：
Tolin DF
中科院分区：
文献类型：
--
作者：
Gilliam CM;Diefenbach GJ;Whiting SE;Tolin DF
本研究评估了暴露与反应预防（EX/RP）阶梯式护理方案治疗强迫症（OCD）的有效性和治疗成本。在目前的公开试验中，患者（N = 14）在六周的过程中开始进行自我指导的EX/RP和最少的治疗师指导（步骤1）。在这个治疗阶段，没有进行治疗师指导的暴露。那些对第一步反应不佳的人继续进行第二步，其中包括每周两次的15次治疗师指导的暴露。本研究结果显示，在一些强迫症患者中使用EX/RP进行阶梯式护理是有希望的，治疗完成者的反应率为88%，耶鲁-布朗强迫症量表（Y-BOCS）得分降低了60%。第1步和第2步完井者的Y-BOCS从治疗前到治疗后均有显著改善。45%的参与者（n = 5）在完成第1步后有反应，导致这些参与者的治疗成本降低。所有对步骤1有反应的参与者在短暂的随访期间都保持了急性获益。限制包括小样本量和高流失率。
This study evaluated the effectiveness and treatment costs associated with a stepped care protocol of exposure and response prevention (EX/RP) for obsessive compulsive disorder (OCD). In the current open trial, patients (N = 14) began with self-directed EX/RP and minimal therapist guidance over the course of six weeks (Step 1). During this phase of treatment, no therapist-directed exposures were conducted. Those who did not respond optimally to Step 1 went on to Step 2, which consisted of 15 sessions of twice-weekly therapist directed exposures. Results of this study show promise for stepped care utilizing EX/RP for some patients with OCD, with a response rate of 88% and a 60% reduction on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score among treatment completers. Significant improvements were found in Y-BOCS from pre to post treatment for both Step 1 and Step 2 completers. Forty-five percent of participants (n = 5) responded following completion of Step 1, resulting in reduced cost of treatment among these participants. All participants who responded to Step 1 maintained acute gains during the brief follow-up period. Limitations include a small sample size and high attrition rate.
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影响因子：
5.9
作者：
JACOBSON, NS;TRUAX, P
通讯作者：
TRUAX, P
影响因子：
4.4
作者：
LEON, AC;SHEAR, MK;KLERMAN, GL
通讯作者：
KLERMAN, GL
影响因子：
5.9
作者：
Otto, MW;Pollack, MH;Maki, KM
通讯作者：
Maki, KM
DOI：
10.2307/3002019
发表时间：
1946-01-01
期刊：
BIOMETRICS BULLETIN
影响因子：
--
作者：
SATTERTHWAITE, FE
通讯作者：
SATTERTHWAITE, FE
影响因子：
4.6
作者：
Brown, TA;Di Nardo, PA;Campbell, LA
通讯作者：
Campbell, LA