Anterior segment optical coherence tomography imaging of conjunctival filtering blebs after glaucoma surgery.

Anterior segment optical coherence tomography imaging of conjunctival filtering blebs after glaucoma surgery.
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DOI:
10.1155/2014/610623
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发表时间:
2014
影响因子:
--
通讯作者:
Mastropasqua L
Mastropasqua L
中科院分区:
生物学3区
文献类型:
--
作者:
Mastropasqua R;Fasanella V;Agnifili L;Curcio C;Ciancaglini M;Mastropasqua L

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时域(TD)和谱域(SD)光学相干断层扫描(OCT)是用于后节和前段(AS)成像的横截面、非接触、高分辨率诊断模式。AS-OCT可对几种眼科疾病的角膜、虹膜、透镜和前房(AC)角进行断层成像。在青光眼中,AS-OCT用于评价疾病发病机制中涉及的AS结构的形态,获得AC的形态测量,评价激光或手术方法的适用性,并评估治疗后的变化。在接受手术的患者中,AS-OCT在评价滤过泡功能方面至关重要,可以进行定性和定量分析。在这一领域,AS-OCT可以帮助临床医生区分功能性和非功能性滤过泡,通过对其宏观形态进行分类,描述滤过泡壁特征,滤过泡腔和巩膜开口。该信息对于在临床方法之前识别滤过失败的迹象以及计划滤过泡失败的管理程序的适当时机至关重要。本文就AS-OCT在结膜滤过泡评价中的应用作一综述。
Time domain (TD) and spectral domain (SD) optical coherence tomography (OCT) are cross-sectional, noncontact, high-resolution diagnostic modalities for posterior and anterior segment (AS) imaging. The AS-OCT provides tomographic imaging of the cornea, iris, lens, and anterior chamber (AC) angle in several ophthalmic diseases. In glaucoma, AS-OCT is utilized to evaluate the morphology of AS structures involved in the pathogenesis of the disease, to obtain morphometric measures of the AC, to evaluate the suitability for laser or surgical approaches, and to assess modifications after treatment. In patients undergoing surgery, AS-OCT is crucial in the evaluation of the filtering bleb functionality, permitting a combined qualitative and quantitative analysis. In this field, AS-OCT may help clinicians in distinguishing between functioning and nonfunctioning blebs by classifying their macroscopic morphology, describing bleb-wall features, bleb cavity, and scleral opening. This information is critical in recognizing signs of filtration failure earlier than the clinical approach and in planning the appropriate timing for management procedures in failing blebs. In this review, we summarize the applications of AS-OCT in the conjunctival bleb assessment.
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