Comparative efficacy and cognitive function of magnetic seizure therapy vs. electroconvulsive therapy for major depressive disorder: a systematic review and meta-analysis.
Comparative efficacy and cognitive function of magnetic seizure therapy vs. electroconvulsive therapy for major depressive disorder: a systematic review and meta-analysis.
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磁惊厥疗法与电休克疗法治疗重度抑郁症的疗效和认知功能比较：一项系统综述和荟萃分析。
DOI：
10.1038/s41398-021-01560-y
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发表时间：
2021-08-21
影响因子：
6.8
通讯作者：
Liu S
中科院分区：
文献类型：
--
作者：
Chen M;Yang X;Liu C;Li J;Wang X;Yang C;Hu X;Li J;Zhao J;Li X;Xu Y;Liu S
磁发作疗法（MST）在抑郁症的治疗中已经确立了疗效，并且在抑郁症的治疗中有越来越多的证据基础。我们对MST在抗抑郁治疗中的疗效及其对认知功能的影响进行了首次系统回顾和荟萃分析（INPLASY注册号：INPLASY202170061）。我们检索了2001年1月1日至2020年12月31日在PubMed、EMBASE、Cochrane图书馆、Web of Science和PsycINFO数据库中发表的英文对照试验。评价过程严格遵循Cochrane偏倚风险评估工具纳入文献，并根据Cochrane系统审稿人手册进行meta分析。在定量综合中保留了来自10项研究的285名患者的数据。结果显示MST与ECT在抗抑郁效果上无显著差异（SDM为- 0.13[- 0.78;0.52]）。与ECT相比，MST的恢复时间（MD为- 5.67[- 9.75;- 1.60]）和定向时间（MD为- 14.67[- 27.96;- 1.41]）更短；在词汇即时回忆（SDM 0.80[0.35;1.25]）、词汇延迟回忆（SDM 0.99[0.01;0.74]）、视觉空间即时记忆（SDM 0.51[0.20;0.83]）、视觉空间延迟记忆（SDM 0.57[0.11;1.02]）和言语流畅性（SDM 0.51[0.20;0.83]）方面，MST组表现出较小的认知障碍。我们的循证研究首次对MST在抗抑郁治疗中的疗效及其对认知功能的影响进行meta分析。结果表明，MST在抗抑郁治疗中的疗效与ECT相当。此外，与ECT相比，MST合并抑郁症患者的认知功能获益更多。
Magnetic seizure therapy (MST) has established efficacy in the treatment of depression and a growing evidence base in the treatment of depression. We conducted the first systematic review and meta-analysis of the efficacy of MST in anti-depressive treatment and its impact on cognitive function (INPLASY registration number: INPLASY202170061). We searched for controlled trials published in English between 1 January 2001 to 31 December 2020 in PubMed, EMBASE, Cochrane Library, Web of Science, and PsycINFO databases. The evaluation process strictly followed the Cochrane bias risk assessment tool into the literature, and Meta-analysis was performed according to the Cochrane System Reviewer’s Manual. Data from a total of 285 patients from 10 studies were retained in the quantitative synthesis. The results showed no significant difference between MST and ECT in the antidepressant effect (SDM −0.13 [−0.78;0.52]). Compared with ECT, MST showed shorter recovery time (MD −5.67 [−9.75; −1.60]) and reorientation time (MD −14.67 [−27.96; −1.41]); and MST showed less cognitive impairment on the immediate recall of words (SDM 0.80 [0.35;1.25]), delayed recall of words (SDM 0.99 [0.01;0.74]), visual-spatial immediate memory (SDM 0.51 [0.20;0.83]), visual-spatial delayed memory (SDM 0.57 [0.11;1.02]), and the verbal fluency (SDM 0.51 [0.20;0.83]). Our evidence-based study is the first meta-analysis on the efficacy of MST in anti-depressive treatment and its effect on cognitive function. It showed that the curative effect of MST in anti-depressive treatment is equivalent to that of ECT. Besides, depressive patients with MST benefit more from cognitive function compared with ECT.
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影响因子：
4.8
作者：
Kayser, Sarah;Bewernick, Bettina H.;Schlaepfer, Thomas E.
通讯作者：
Schlaepfer, Thomas E.
影响因子：
7.4
作者：
Fitzgerald, Paul B.;Hoy, Kate E.;Daskalakis, Zafiris J.
通讯作者：
Daskalakis, Zafiris J.
影响因子：
7.6
作者：
Lisanby, SH;Luber, B;Sackeim, HA
通讯作者：
Sackeim, HA
DOI：
10.1016/j.pmip.2019.04.003
发表时间：
2019-11-01
期刊：
Personalized medicine in psychiatry
影响因子：
--
作者：
Kallioniemi, Elisa;McClintock, Shawn M;Lisanby, Sarah H
通讯作者：
Lisanby, Sarah H
影响因子：
3.3
作者：
Dwork, A. J.;Christensen, J. R.;Lisanby, S. H.
通讯作者：
Lisanby, S. H.