Resin-based composite performance: are there some things we can't predict?
Resin-based composite performance: are there some things we can't predict?
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DOI：
10.1016/j.dental.2012.06.013
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发表时间：
2013-01
期刊：
影响因子：
5
通讯作者：
Ferracane, Jack L.
中科院分区：
文献类型：
--
作者：
Ferracane, Jack L.
关键词：
本手稿的目的是解决以下问题：为什么直接牙科复合修复材料在临床上失败？哪些测试可能适合预测临床表现？体外测试与临床表现相关吗？回顾了与牙科复合修复材料的临床和实验室性能相关的文献。牙科复合材料修复体失败和更换的主要原因为确定可能对临床结果影响最大的特定材料的特性提供了指导。很少有研究表明牙科复合材料的物理或机械性能的实验室测试与临床性能之间的相关性。确实有证据表明临床磨损与弯曲强度、断裂韧性和聚合物基质的转化程度相关。有证据表明边缘破坏与断裂韧性有关。尽管几乎没有确凿的证据，但人们预计临床断裂和磨损与抗疲劳性有关。仅存在极少的证据将实验室中的边际质量和粘合强度与粘合牙科复合材料的临床性能相关联。使用临床试验来评估新的牙科复合材料配方的性能既昂贵又耗时，并且能够根据单个或多个实验室测试来预测临床结果将是理想的。然而，尽管存在某些相关性，但牙科复合材料的总体临床成功是多因素的，因此即使通过一系列体外测试方法也不太可能准确预测。
The objective of this manuscript is to address the following questions: Why do direct dental composite restorative materials fail clinically? What tests may be appropriate for predicting clinical performance? Does in vitro testing correlate with clinical performance? The literature relating to the clinical and laboratory performance of dental composite restorative materials was reviewed. The main reasons for failure and replacement of dental composite restorations provided the guidance for identifying specific material’s properties that were likely to have the greatest impact on clinical outcomes. There are few examples of studies showing correlation between laboratory tests of physical or mechanical properties and clinical performance of dental composites. Evidence does exist to relate clinical wear to flexure strength, fracture toughness and degree of conversion of the polymer matrix. There is evidence relating marginal breakdown to fracture toughness. Despite the fact that little confirmatory evidence exists, there is the expectation that clinical fracture and wear relates to resistance to fatigue. Only minimal evidence exists to correlate marginal quality and bond strength in the laboratory with clinical performance of bonded dental composites. The use of clinical trials to evaluate new dental composite formulations for their performance is expensive and time consuming, and it would be ideal to be able to predict clinical outcomes based on a single or multiple laboratory tests. However, though certain correlations exist, the overall clinical success of dental composites is multi-factorial and therefore is unlikely to be predicted accurately by even a battery of in vitro test methods.
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影响因子：
7.6
作者：
Ferracane, JL;Mitchem, JC;Todd, R
通讯作者：
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DOI：
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发表时间：
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