Short- and long-term effects of UV radiation on the pigmentation of human skin.

Short- and long-term effects of UV radiation on the pigmentation of human skin.
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DOI:
10.1038/jidsymp.2009.10
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发表时间:
2009-08
影响因子:
--
通讯作者:
Hearing, Vincent J.
Hearing, Vincent J.
中科院分区:
其他
文献类型:
--
作者:
Coelho, Sergio G.;Choi, Wonseon;Brenner, Michaela;Miyamura, Yoshinori;Yamaguchi, Yuji;Wolber, Rainer;Smuda, Christoph;Batzer, Jan;Kolbe, Ludger;Ito, Shosuke;Wakamatsu, Kazumasa;Zmudzka, Barbara Z.;Beer, Janusz Z.;Miller, Sharon A.;Hearing, Vincent J.

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The incidence of skin cancer, including cutaneous melanoma, has risen substantially in recent years, and epidemiological and laboratory studies demonstrate that ultraviolet (UV) radiation is a major causative factor for this increase. UV damage also underlies photoaging of the skin, and those deleterious effects of UV can be, in part, prevented in skin with higher levels of constitutive pigmentation. We review the findings of a series of clinical studies we have made in recent years regarding the rapid and the long-term responses of the pigmentary system in human skin to UV exposure. Key words: ultraviolet, skin, photoprotection, pigmentation, photoaging
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