Depression and executive dysfunction contribute to a metamemory deficit among individuals with methamphetamine use disorders.
Depression and executive dysfunction contribute to a metamemory deficit among individuals with methamphetamine use disorders.
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DOI：
10.1016/j.addbeh.2014.08.007
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发表时间：
2015-01
影响因子：
4.4
通讯作者：
Woods, S. P.
中科院分区：
文献类型：
--
作者：
Casaletto, K. B.;Obermeit, L.;Morgan, E. E.;Weber, E.;Franklin, D. R.;Grant, I.;Woods, S. P.
慢性甲基苯丙胺（MA）使用与学习和记忆的中度缺陷有关，但MA使用者意识到这种记忆缺陷（即元记忆）的程度尚不清楚。在目前的研究中，195名终身使用MA诊断的参与者（MA+）和195名未使用MA的比较受试者（MA -）接受了全面的神经精神病学研究评估，包括基于表现和自我报告的情景记忆测量。MA使用障碍、重度抑郁症（MDD）及其相互作用与元记忆功能有独特的关联，因此MDD增加了MA+参与者出现元记忆缺陷的可能性。在MA组中，高估自己记忆能力的个体表现出更大的执行功能障碍和更低的认知储备。慢性MA使用与记忆获取和回忆的客观缺陷意识降低有关，重度抑郁症的存在尤其加剧了这种缺陷。努力提高记忆的准确性和代偿记忆策略的部署可能有利于药物滥用治疗的结果。
Chronic methamphetamine (MA) use is associated with moderate deficits in learning and memory, but the extent to which MA users are aware of such memory deficits (i.e., metamemory) is not known. In the current study, 195 participants with lifetime MA use diagnoses (MA+) and 195 non-MA-using comparison subjects (MA−) underwent comprehensive neuropsychiatric research assessments, including performance-based and self-report measures of episodic memory. MA use disorders, major depressive disorder (MDD), and their interaction were uniquely associated with metamemory functioning, such that MDD increased the likelihood of a metamemory deficit among the MA+ participants. Within the MA group, individuals who over-estimated their memory abilities demonstrated greater executive dysfunction and lower cognitive reserve. Chronic MA use is associated with reduced awareness of objective deficits in memory acquisition and recall, which is particularly exacerbated by the presence of major depression. Efforts to enhance metamemory accuracy and deployment of compensatory mnemonic strategies may benefit substance abuse treatment outcomes.
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DOI：
10.1017/s1355617704101021
发表时间：
2004-01-01
影响因子：
2.6
作者：
Rippeth, JD;Heaton, RK;Grant, I
通讯作者：
Grant, I
影响因子：
3.2
作者：
Heaton, Robert K.;Franklin, Donald R.;Ellis, Ronald J.;McCutchan, J. Allen;Letendre, Scott L.;LeBlanc, Shannon;Corkran, Stephanie H.;Duarte, Nichole A.;Clifford, David B.;Woods, Steven P.;Collier, Ann C.;Marra, Christina M.;Morgello, Susan;Mindt, Monica Rivera;Taylor, Michael J.;Marcotte, Thomas D.;Atkinson, J. Hampton;Wolfson, Tanya;Gelman, Benjamin B.;McArthur, Justin C.;Simpson, David M.;Abramson, Ian;Gamst, Anthony;Fennema-Notestine, Christine;Jernigan, Terry L.;Wong, Joseph;Grant, Igor
通讯作者：
Grant, Igor
影响因子：
1.9
作者：
NIEDEREHE, G;YODER, C
通讯作者：
YODER, C
DOI：
10.1176/appi.neuropsych.11080192
发表时间：
2012
期刊：
The Journal of neuropsychiatry and clinical neurosciences
影响因子：
--
作者：
Cattie JE;Woods SP;Iudicello JE;Posada C;Grant I;TMARC Group
通讯作者：
TMARC Group
影响因子：
4.2
作者：
Weber, Erica;Blackstone, Kaitlin;Iudicello, Jennfer E.;Morgan, Erin E.;Grant, Igor;Moore, David J.;Woods, Steven Paul
通讯作者：
Woods, Steven Paul