Bridging the Gap: Plant‐Endophyte Interactions as a Roadmap to Understanding Small‐Molecule Communication in Marine Microbiomes
Bridging the Gap: Plant‐Endophyte Interactions as a Roadmap to Understanding Small‐Molecule Communication in Marine Microbiomes
复制标题
弥合差距:植物与内生菌相互作用作为了解海洋微生物组中小分子通讯的路线图
DOI:
10.1002/cbic.202000064
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发表时间:
2020
期刊:
影响因子:
3.2
通讯作者:
Balunas, Marcy J.
中科院分区:
文献类型:
--
作者:
Samples, Robert M.;Balunas, Marcy J.
Probing the composition of the microbiome and its association with health and disease states is more accessible than ever due to the rise of affordable sequencing technology. Despite advances in our ability to identify members of symbiont communities, untangling the chemical signaling that they use to communicate with host organisms remains challenging. In order to gain a greater mechanistic understanding of how the microbiome impacts health, and how chemical ecology can be leveraged to advance small‐molecule drug discovery from microorganisms, the principals governing communication between host and symbiont must be elucidated. Herein, we review common modes of interkingdom small‐molecule communication in terrestrial and marine environments, describe the differences between these environments, and detail the advantages and disadvantages for studies focused on the marine environment. Finally, we propose the use of plant‐endophyte interactions as a stepping stone to a greater understanding of similar interactions in marine invertebrates, and ultimately in humans.
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DOI:
--
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期刊:
影响因子:
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