The neuronal organization of the retina.

The neuronal organization of the retina.
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DOI:
10.1016/j.neuron.2012.10.002
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发表时间:
2012-10-18
期刊:
影响因子:
16.2
通讯作者:
Masland RH
Masland RH
中科院分区:
医学1区
文献类型:
--
作者:
Masland RH

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哺乳动物视网膜由超过 60 种不同类型的神经元组成,每种神经元在处理视觉图像中发挥着特定的作用。它们分为三个主要阶段。第一个将视杆细胞和视锥细胞感光器的输出分解为约 12 个并行信息流。第二个将这些流连接到特定类型的视网膜神经节细胞。第三种结合双极细胞和无长突细胞活动,创建视觉世界的多种编码(大约有 20 种),并由视网膜传输到大脑。视觉输入的新转变不断被发现:至少一半发送到大脑的编码(神经节细胞反应选择性)仍有待发现。视网膜输出的这种多样性尚未纳入我们对高级视觉功能的理解中。
The mammalian retina consists of neurons of >60 distinct types, each playing a specific role in processing visual images. They are arranged in three main stages. The first decomposes the outputs of the rod and cone photoreceptors into ~12 parallel information streams. The second connects these streams to specific types of retinal ganglion cells. The third combines bipolar and amacrine cell activity to create the diverse encodings of the visual world—roughly 20 of them—that the retina transmits to the brain. New transformations of the visual input continue to be found: at least half of the encodings sent to the brain (ganglion cell response selectivities) remain to be discovered. This diversity of the retina’s outputs has yet to be incorporated into our understanding of higher visual function.
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