Nocturnal growth hormone secretory dynamics are altered after resistance exercise: deconvolution analysis of 12-hour immunofunctional and immunoreactive isoforms.

Nocturnal growth hormone secretory dynamics are altered after resistance exercise: deconvolution analysis of 12-hour immunofunctional and immunoreactive isoforms.
复制标题

抗阻运动后夜间生长激素分泌动态发生改变:12 小时免疫功能和免疫反应亚型的反卷积分析。

DOI:
10.1152/ajpregu.00854.2005
复制
发表时间:
2006
期刊:
American journal of physiology. Regulatory, integrative and comparative physiology
影响因子:
--
通讯作者:
Nindl,BradleyC
Nindl,BradleyC
中科院分区:
--
文献类型:
--
作者:
Tuckow,AlexanderP;Rarick,KevinR;Kraemer,WilliamJ;Marx,JamesO;Hymer,WesleyC;Nindl,BradleyC

文献摘要

参考文献

被引文献

相似文献

为了表征日间运动对随后过夜生长激素 (GH) 分泌和消除动态的影响,对血清进行采样,并在对照 (CON) 条件下以及在 1500 至 1700 进行 50 组阻力运动方案 (EX) 后,每 10 分钟测量一次 GH,持续 12 小时(1800 至 0600)。使用传统免疫反应 (IR) 和免疫功能 (IF) 测定法测量 GH,并通过多参数反卷积分析。 EX 导致夜间分泌突发频率较高 [CON: 7.6 (SD 2.4) < EX: 9.4 (2.2) 每 12 小时突发,P= 0.005],但平均突发质量 [CON: 9.2 (4.7) > EX: 6.0 (2.9) μg/l,P= 0.019] 和分泌率 [CON: 0.68 (0.29) > EX: 0.48 (0.23) 微克/升/分钟;P= 0.015;方差分析主效应表示]。 EX 后的近似熵 (ApEn) 更大,表明 GH 释放过程不如 CON 有序。 IF GH 的估计半衰期显着低于 IR GH [IF:15.3 (1.1) < IR 19.8 (1.6) 分钟,P < 0.001],但 CON 和 EX 条件之间相似(~17 分钟)。尽管分泌动态发生变化,但不同条件下 12 小时平均 GH 浓度和综合 GH 浓度相似。结果表明,尽管在 CON 和 EX 条件下过夜分泌的 GH 总量在数量上相似,但抗阻运动通过减弱爆发质量和幅度但增加爆发频率来改变分泌动态。
To characterize the effects of daytime exercise on subsequent overnight growth hormone (GH) secretion and elimination dynamics, serum was sampled, and GH was measured every 10 min for 12 h (1800 to 0600) in a control (CON) condition and after a 50-set resistance exercise protocol (EX) from 1500 to 1700. GH was measured with a conventional immunoreactive (IR) and an immunofunctional (IF) assay, and values were analyzed via a multi-parameter deconvolution analysis. EX resulted in a higher overnight secretory burst frequency [CON: 7.6 (SD 2.4) < EX: 9.4 (2.2) bursts per 12 h,P= 0.005] but lower mean burst mass [CON: 9.2 (4.7) > EX: 6.0 (2.9) μg/l,P= 0.019] and secretory rate [CON: 0.68 (0.29) > EX: 0.48 (0.23) μg/l/min;P= 0.015; ANOVA main effect means presented]. Approximate entropy (ApEn) was greater after EX, indicating a less orderly GH release process than CON. The estimated half-life of IF GH was significantly lower than IR GH [IF: 15.3 (1.1) < IR 19.8 (1.6) min,P< 0.001] but similar between the CON and EX conditions (∼17 min). Despite the changes in secretory dynamics, 12-h mean and integrated GH concentrations were similar between conditions. The results suggest that although quantitatively similar total amounts of GH are secreted overnight in CON and EX conditions, resistance exercise alters the dynamics of secretion by attenuating burst mass and amplitude yet increasing burst frequency.
急性运动强度对男性脉动生长激素释放的影响。
DOI: 10.1152/jappl.1999.87.2.498
发表时间: 1999
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
作者:
Pritzlaff,CJ;Wideman,L;Weltman,JY;Abbott,RD;Gutgesell,ME;Hartman,ML;Veldhuis,JD;Weltman,A
通讯作者: Weltman,A
DOI: 10.1210/jcem.85.11.6957
发表时间: 2000-11
期刊: The Journal of clinical endocrinology and metabolism
影响因子: --
作者:
T. Laursen;A. Flyvbjerg;J. Jørgensen;R. Baxter;J. Christiansen
通讯作者: T. Laursen;A. Flyvbjerg;J. Jørgensen;R. Baxter;J. Christiansen
耐力训练会放大生长激素的脉动释放:训练强度的影响。
DOI: 10.1152/jappl.1992.72.6.2188
发表时间: 1992
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
作者:
Weltman,A;Weltman,JY;Schurrer,R;Evans,WS;Veldhuis,JD;Rogol,AD
通讯作者: Rogol,AD
DOI: 10.1210/endo-123-2-1053
发表时间: 1988-08-01
期刊: ENDOCRINOLOGY
影响因子: 4.8
作者:
MAITER, D;UNDERWOOD, LE;KETELSLEGERS, JM
通讯作者: KETELSLEGERS, JM
生长激素分子异质性与运动
DOI: --
发表时间: 2003
影响因子: 5.7
作者:
B. Nindl;W. Kraemer;J. Marx;A. P. Tuckow;W. Hymer
通讯作者: W. Hymer