Flavonoids and alkaloids from Lysionotus pauciflorus (Gesneriaceae)

Flavonoids and alkaloids from Lysionotus pauciflorus (Gesneriaceae)
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Lysionotus pauciflorus(苦苣苔科)中的黄酮类化合物和生物碱

DOI:
10.1016/j.bse.2022.104447
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发表时间:
2022-08
期刊:
Elsevier
影响因子:
--
通讯作者:
Xiaojiang Hao
Xiaojiang Hao
中科院分区:
其他
文献类型:
--
作者:
Wei Gu;Jiayu Zhang;Huanyang Li;Junlei Chen;Ruixuan Xie;Chunmao Yuan;Liejun Huang;Xiaojiang Hao

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The phytochemical investigation on the whole plant of Lysionotus pauciflorus led to the isolation of a new flavonoid ( 1 ), along with eight known flavonoids ( 2 – 9 ), as well as five alkaloids ( 10 – 14 ). Their structures were elucidated based on extensive spectroscopic methods ( 1 D and 2 D NMR, HRESIMS, IR, and UV experiments), coupled with comparison with literature data. Among these known compounds, compounds 2 , 4 – 6 , 10 – 14 were isolated from L. pauciflorus for the first time. What is particularly exciting is that alkaloid compounds, which possessed indole skeleton, were found in Gesneriaceae plants for the first time. The chemotaxonomic significance of these isolated compounds has also been discussed. The highly oxygenated flavones identified in the plant may be used as chemotaxonomic marker of Lysionotus . • 14 compounds were isolated from the whole plant of Lysionotus pauciflorus. • Compound 1 was a new flavonoid. • Compounds 2 , 4 – 6 , 10 – 14 were isolated from L. pauciflorus for the first time. • The alkaloids were found in Gesneriaceae plants for the first time. • Highly oxygenated flavones can be recognized as typical biomarkers for the genus Lysionotus.
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