Responsibility and Laboratory Animal Research Governance.
Responsibility and Laboratory Animal Research Governance.
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DOI：
10.1177/0162243917727866
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Hartley S
中科院分区：
文献类型：
--
作者：
McLeod C;Hartley S
在实验和研究中使用动物仍然极具争议。实验动物研究治理提供了指导和监管框架，以监督实验动物的使用和福利，并在很大程度上依赖于替代、减少和改进（3Rs）原则来证明责任。然而，3r的应用被批评为焦点过于狭窄，并关闭了有关动物实验室研究目的的社会关注和政治问题。这些批评挑战了实验室动物研究管理责任的合法性，并呼吁采取新的方法。随着“负责任的研究与创新”（Responsible Research and Innovation， RRI）议程的出现，我们研究了在有争议的动物研究治理领域，是否可以通过RRI检查3r来加强责任的概念。我们的分析表明，RRI有潜力在三个关键方面帮助增强3r：认识到需要在动物研究治理中纳入更广泛的专家和公众；强调动物研究科学家不仅要考虑角色，还要考虑社会责任的重要性；并承认动物研究引发的政治问题。
The use of animals in experiments and research remains highly contentious. Laboratory animal research governance provides guidance and regulatory frameworks to oversee the use and welfare of laboratory animals and relies heavily on the replacement, reduction, and refinement (3Rs) principles to demonstrate responsibility. However, the application of the 3Rs is criticized for being too narrow in focus and closing down societal concerns and political questions about the purpose of animal laboratory research. These critiques challenge the legitimacy of responsibility in laboratory animal research governance and call for new approaches. With the advent of the "Responsible Research and Innovation" (RRI) agenda, we investigate whether the notion of responsibility in the controversial area of animal research governance could be enhanced by examining the 3Rs through RRI. Our analysis reveals RRI has the potential to helpfully augment the 3Rs in three key ways: recognizing the need to include a broader range of experts and publics in animal research governance; emphasizing the importance for animal research scientists of taking societal, and not just role, responsibilities into account; and acknowledging the political questions animal research raises.
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影响因子：
3
作者：
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通讯作者：
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影响因子：
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作者：
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发表时间：
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