Assessing the economic attractiveness of coronary artery revascularization in chronic kidney disease patients.

Assessing the economic attractiveness of coronary artery revascularization in chronic kidney disease patients.
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DOI:
10.1007/s10916-008-9190-4
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发表时间:
2009-08
影响因子:
5.3
通讯作者:
Mark, Daniel B.
Mark, Daniel B.
中科院分区:
医学3区
文献类型:
--
作者:
Eisenstein, Eric L.;Sun, Jie L.;Anstrom, Kevin J.;DeLong, Elizabeth R.;Szczech, Lynda A.;Mark, Daniel B.

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慢性肾脏疾病(CKD)与冠心病(CAD)患者的发病率和死亡率增加有关。我们比较了合并和不合并慢性肾功能不全的患者行冠状动脉血管重建术的经济吸引力。我们的研究对象包括1996年至2001年间在杜克大学接受心导管术的6218名严重冠心病患者,并随访至2002年。我们调查了CKD(肌酐清除量和60毫升/分钟)对我们的CAD人群3年存活率和医疗费用的影响。冠状动脉旁路移植术(CABG)对于所有左主干病变患者、无CKD的三支冠状动脉病变患者和合并CKD的两支冠状动脉病变患者来说,是一种比经皮冠状动脉介入治疗(PCI)或内科治疗更具经济吸引力的选择。与冠状动脉旁路手术或经皮冠状动脉介入治疗相比,内科治疗是一种经济上有吸引力的策略,适用于有CKD的三支血管CAD患者、无CKD的两支血管CAD患者和所有单支冠状动脉病变患者。
Chronic kidney disease (CKD) is associated with increased morbidity and mortality in coronary artery disease (CAD) patients. We compared the economic attractiveness of CAD revascularization procedures in patients with and without CKD. Our population included 6218 patients with significant CAD undergoing cardiac catheterization at Duke University between 1996 and 2001, with follow-up through 2002. We investigated the influence of CKD (creatinine clearance < 60 mL/min) upon 3-year survival and medical costs in our CAD population. Coronary artery bypass graft (CABG) surgery was an economically attractive alternative vs. percutaneous coronary intervention (PCI) or medical therapy for all patients with left main disease, three-vessel CAD patients without CKD, and two-vessel CAD patients with CKD. Medical therapy was an economically attractive strategy vs. CABG surgery or PCI for three-vessel CAD patients with CKD, two-vessel CAD patients without CKD, and all single-vessel CAD patients.
DOI: 10.1056/nejm199701093360203
发表时间: 1997-01-09
影响因子: 158.5
作者:
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