Readiness for behaviour change in non-alcoholic fatty liver disease: implications for multidisciplinary care models.
Readiness for behaviour change in non-alcoholic fatty liver disease: implications for multidisciplinary care models.
复制标题
DOI：
10.1111/liv.12483
复制
发表时间：
2015-03
期刊：
影响因子：
--
通讯作者：
Sanyal AJ
中科院分区：
文献类型：
--
作者：
Stewart KE;Haller DL;Sargeant C;Levenson JL;Puri P;Sanyal AJ
体重管理是超重/肥胖非酒精性脂肪性肝病（NAFLD）患者治疗的基石。这项探索性研究旨在：（i）评估改变体重相关行为的准备情况;（ii）评估可能干扰体重减轻的社会心理特征;（iii）评估基线社会心理特征如何与接受标准医疗护理的NAFLD患者的6个月体重变化相关。本研究的目的是发展关于心理社会因素和体重之间关系的假设，用于未来的充分动力研究和临床干预。58名超重/肥胖的NAFLD参与者完成了人格、精神症状和行为改变准备的基线测量，并在标准护理中随访6个月。三分之一的参与者（31.0%）对改变与体重有关的行为不感兴趣; 58.6%的人正在考虑改变，10.4%的人正在积极努力或准备改变。6个月的体重变化不显著，与基线变化准备无关。在6个月的随访中，抑郁、低焦虑和高神经质与体重增加相关，效应量从小到大。虽然参与者接受了营养教育和指导，但很少有人处于积极的变化阶段。虽然改变的准备并不能预测随后的体重变化，但人格因素和精神症状与体重结果相关。综合多学科的方法，解决精神病的需要，并提供减肥的行为支持，可以帮助NAFLD患者实施持续的生活方式改变。
Weight management is a cornerstone of treatment for overweight/obese persons with non-alcoholic fatty liver disease (NAFLD). This exploratory study sought to: (i) evaluate readiness to change weight-related behaviours; (ii) assess psychosocial characteristics that may interfere with weight loss; and (iii) evaluate how baseline psychosocial features associate with 6-month change in weight in persons with NAFLD receiving standard medical care. The purpose of this investigation was to develop hypotheses regarding relationships between psychosocial factors and weight for use in future fully powered studies and clinical interventions Fifty-eight overweight/obese participants with NAFLD completed baseline measures of personality, psychiatric symptoms and readiness for behaviour change and were followed up for 6 months in standard care. One-third of participants (31.0%) were not interested in making weight-related behaviour changes; 58.6% were considering making a change, and 10.4% of individuals were actively working on or preparing to change. Six-month change in weight was non-significant and was not associated with baseline readiness for change. Depression, low conscientiousness and high neuroticism were associated with higher weight at 6-month follow-up with small to large effect sizes. Although participants received nutritional education and guidance, very few individuals presented in the active stage of change. Although readiness for change did not predict subsequent change in weight, personality factors and psychiatric symptoms were associated with weight outcomes. Integrated multidisciplinary approaches that address psychiatric needs and provide behavioural support for weight loss may help patients with NAFLD implement sustained lifestyle changes.
登录
查看更多内容
DOI：
10.1056/nejmoa0907929
发表时间：
2010-05-06
期刊：
The New England journal of medicine
影响因子：
--
作者：
Sanyal AJ;Chalasani N;Kowdley KV;McCullough A;Diehl AM;Bass NM;Neuschwander-Tetri BA;Lavine JE;Tonascia J;Unalp A;Van Natta M;Clark J;Brunt EM;Kleiner DE;Hoofnagle JH;Robuck PR;NASH CRN
通讯作者：
NASH CRN
影响因子：
4.2
作者：
Amodei, N;Lamb, RJ
通讯作者：
Lamb, RJ
影响因子：
4.2
作者：
Field, Craig A.;Adinoff, Bryon;Carroll, Kathleen M.
通讯作者：
Carroll, Kathleen M.
影响因子：
7.6
作者：
Sutin, Angelina R.;Ferrucci, Luigi;Terracciano, Antonio
通讯作者：
Terracciano, Antonio
影响因子：
13.5
作者：
Kleiner, DE;Brunt, EM;Sanyal, AJ
通讯作者：
Sanyal, AJ