Web-Based Cognitive Testing in Psychiatric Research: Validation and Usability Study.
Web-Based Cognitive Testing in Psychiatric Research: Validation and Usability Study.
复制标题
DOI：
10.2196/28233
复制
发表时间：
2022-02-10
影响因子：
7.4
通讯作者：
Walters JTR
中科院分区：
文献类型：
--
作者：
Lynham AJ;Jones IR;Walters JTR
认知障碍是许多精神疾病的特征，并影响功能。对精神疾病进行认知研究的一个障碍是缺乏大量的跨疾病数据集。然而，认知数据的收集可能在逻辑上具有挑战性且昂贵。基于网络的收集可能是一种替代方案，但是，很少有人知道谁做，不完成基于网络的认知评估精神病学研究。本研究的目的是开发一个基于网络的认知电池用于精神病学研究，验证电池对测量和治疗研究，以提高认知精神分裂症（MATRICS）共识认知电池，并比较参与者的特点谁选择参加与那些没有参加的个人。任务是由多脑项目开发的，并被选择来测量由MATRICS倡议指定的领域。我们对65名患有精神分裂症、双相情感障碍、抑郁症或无精神疾病史的参与者进行了交叉验证研究，以将基于网络的任务与MATRICS共识认知成套测验进行比较。在验证之后，我们邀请了来自2项正在进行的大型遗传研究的参与者，这些研究招募了患有精神疾病的参与者来完成电池，并评估了参与者的人口统计学和临床特征。基于网络的任务和MATRICS任务之间的相关性在0.26和0.73之间。在961名参与者中，887人（92.3%）完成了至少一项基于网络的任务，644人（67%）完成了所有任务，表明完成率足够。网络参与的预测因素包括女性（比值比[OR] 1.3，95% CI 1.07-1.58），非白色欧洲人种族（OR 0.66，95% CI 0.46-0.96），教育水平较高（OR 1.19，95% CI 1.11-1.29），诊断为进食障碍（OR 2.17，95% CI 1.17-4）或抑郁和焦虑（OR 5.12，95% CI 3.38-7.83），以及未诊断为精神分裂症（OR 0.59，95% CI 0.35-0.94）。电池性能较低与功能较差相关（B=-1.76，SE 0.26; P<.001）。我们的研究结果为远程测试心理健康研究的认知功能的优点和缺点提供了有价值的见解。
Cognitive impairments are features of many psychiatric disorders and affect functioning. A barrier to cognitive research on psychiatric disorders is the lack of large cross-disorder data sets. However, the collection of cognitive data can be logistically challenging and expensive. Web-based collection may be an alternative; however, little is known about who does and does not complete web-based cognitive assessments for psychiatric research. The aims of this study are to develop a web-based cognitive battery for use in psychiatric research, validate the battery against the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery, and compare the characteristics of the participants who chose to take part with those of the individuals who did not participate. Tasks were developed by The Many Brains Project and selected to measure the domains specified by the MATRICS initiative. We undertook a cross-validation study of 65 participants with schizophrenia, bipolar disorder, depression, or no history of psychiatric disorders to compare the web-based tasks with the MATRICS Consensus Cognitive Battery. Following validation, we invited participants from 2 large ongoing genetic studies, which recruited participants with psychiatric disorders to complete the battery and evaluated the demographic and clinical characteristics of those who took part. Correlations between web-based and MATRICS tasks ranged between 0.26 and 0.73. Of the 961 participants, 887 (92.3%) completed at least one web-based task, and 644 (67%) completed all tasks, indicating adequate completion rates. Predictors of web-based participation included being female (odds ratio [OR] 1.3, 95% CI 1.07-1.58), ethnicity other than White European (OR 0.66, 95% CI 0.46-0.96), higher levels of education (OR 1.19, 95% CI 1.11-1.29), diagnosis of an eating disorder (OR 2.17, 95% CI 1.17-4) or depression and anxiety (OR 5.12, 95% CI 3.38-7.83), and absence of a diagnosis of schizophrenia (OR 0.59, 95% CI 0.35-0.94). Lower performance on the battery was associated with poorer functioning (B=−1.76, SE 0.26; P<.001). Our findings offer valuable insights into the advantages and disadvantages of testing cognitive function remotely for mental health research.
登录
查看更多内容
DOI：
10.1017/s1355617702860131
发表时间：
2002-09-01
影响因子：
2.6
作者：
Bright, P;Jaldow, E;Kopelman, MD
通讯作者：
Kopelman, MD
影响因子：
8.2
作者：
Hartshorne JK;Germine LT
通讯作者：
Germine LT
影响因子：
9.9
作者：
Darby, D. G.;Fredrickson, J.;Brodtmann, A.
通讯作者：
Brodtmann, A.
影响因子：
11.3
作者：
Frigerio, E;Burt, DM;Perrett, DI
通讯作者：
Perrett, DI
DOI：
10.1080/13803395.2017.1339017
发表时间：
2018-01-01
影响因子：
2.2
作者：
Feenstra, Heleen E. M.;Murre, Jaap M. J.;Schagen, Sanne B.
通讯作者：
Schagen, Sanne B.