Cell migration in the postembryonic development of the fish lateral line.
Cell migration in the postembryonic development of the fish lateral line.
复制标题
鱼侧线胚胎后发育中的细胞迁移。
作者：
Dora Sapède;N. Gompel;C. Dambly‐Chaudière;A. Ghysen
我们在细胞水平上研究了斑马鱼后侧线的胚后发育。我们发现，第一波的次级神经瘤是由一个迁移的原基，primII。该原基起源于头部区域，非常类似于胚胎发生期间形成主线的原基。PrimII对后侧线的外侧支和背侧支都有贡献。一旦它们被原基沉积，分化中的神经瘤诱导覆盖的表皮细胞特化为成孔环，整个结构开始向腹侧迁移穿过上皮。因此，最终的二维模式取决于两个正交过程的组合：前后波的神经肥大形成和背腹迁移的个别神经肥大。最后，我们研究如何一般这些迁移过程可以通过描述两种鱼类具有非常不同的成年模式，Astyanax fasciatus（墨西哥盲洞穴鱼）和Oryzias latipes（青）。我们发现，它们的主要模式与在斑马鱼胚胎中观察到的模式几乎相同，并且它们的胚后生长依赖于我们在斑马鱼的情况下记录的相同的迁移过程组合。
We examine at the cellular level the postembryonic development of the posterior lateral line in the zebrafish. We show that the first wave of secondary neuromasts is laid down by a migrating primordium, primII. This primordium originates from a cephalic region much like the primordium that formed the primary line during embryogenesis. PrimII contributes to both the lateral and the dorsal branches of the posterior lateral line. Once they are deposited by the primordium, the differentiating neuromasts induce the specialisation of overlying epidermal cells into a pore-forming annulus, and the entire structure begins to migrate ventrally across the epithelium. Thus the final two-dimensional pattern depends on the combination of two orthogonal processes: anteroposterior waves of neuromast formation and dorsoventral migration of individual neuromasts. Finally, we examine how general these migratory processes can be by describing two fish species with very different adult patterns, Astyanax fasciatus (Mexican blind cavefish) and Oryzias latipes (medaka). We show that their primary patterns are nearly identical to that observed in zebrafish embryos, and that their postembryonic growth relies on the same combination of migratory processes that we documented in the case of the zebrafish.
影响因子：
56.9
作者：
COLLAZO, A;FRASER, SE;MABEE, PM
通讯作者：
MABEE, PM