Effect of exercise training and detraining on bone mineral density in postmenopausal women with osteoporosis

Effect of exercise training and detraining on bone mineral density in postmenopausal women with osteoporosis
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运动训练和停止训练对绝经后骨质疏松症女性骨密度的影响

DOI:
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发表时间:
2001
影响因子:
1.7
通讯作者:
S. Ichimura
S. Ichimura
中科院分区:
医学4区
文献类型:
--
作者:
J. Iwamoto;T. Takeda;S. Ichimura

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摘要我们研究了运动训练和停训对绝经后骨质疏松妇女骨密度的影响。35例绝经后骨质疏松症妇女,年龄53-77岁,随机分为3组:对照组(n = 20),运动训练2年组(n = 8),运动训练1年+停训1年组(n = 7)。运动训练包括每日快走和体操训练。所有受试者每天供应乳酸钙2.0 g和1α-羟基维生素D3 1 μg。双能X线骨密度仪(DXA)测量的初始腰椎BMD在三组之间无显著差异。与基线相比,运动训练组在1年和2年时以及停训组在1年时BMD的平均百分比变化显著高于对照组,停训组和对照组在2年时无显著差异。这些结果表明,我们的运动训练计划导致绝经后骨质疏松症妇女的腰椎骨密度显着增加与对照组相比,但骨密度恢复到一个水平,这是没有显着不同的对照组与停止训练。需要持续的运动训练来维持通过运动训练获得的骨量。
Abstract We examined the effect of exercise training and detraining on bone mineral density (BMD) in postmenopausal women with osteoporosis. Thirty-five postmenopausal women with osteoporosis, aged 53–77 years, were randomly assigned to three groups: a control group (n = 20), a 2-year exercise training group (n = 8), and an 1-year exercise training plus 1-year detraining group (n = 7). Exercise training consisted of daily brisk walking and gymnastic training. Calcium lactate, 2.0 g, and 1α-hydroxyvitamin D3, 1 μg were supplied daily to all subjects. No significant differences in initial lumbar BMD, measured by dual-energy X-ray absorptiometry (DXA) were found among the three groups. The mean percent change in BMD compared with the baseline was significantly higher at 1 and 2 years in the exercise training group and at 1 year in the detraining group than in the control group, and did not differ significantly at 2 years between the detraining and control groups. These findings indicate that our exercise training program led to a significant increase in lumbar BMD in postmenopausal women with osteoporosis compared with the control, but that the BMD reverted toward a level that was not significantly different from the control with detraining. Continued exercise training is needed to maintain the bone mass gained through exercise training.
DOI: 10.7326/0003-4819-108-6-824
发表时间: 1988-06-01
影响因子: 39.2
作者:
DALSKY, GP;STOCKE, KS;BIRGE, SJ
通讯作者: BIRGE, SJ