Temporal daily associations between pain and sleep in adolescents with chronic pain versus healthy adolescents.
Temporal daily associations between pain and sleep in adolescents with chronic pain versus healthy adolescents.
复制标题
作者：
Lewandowski AS;Palermo TM;De la Motte S;Fu R
患有慢性疼痛的青少年经常报告睡眠障碍，特别是睡眠持续时间短，夜间醒来，睡眠质量差。先前的研究一直受限于对主观报告的睡眠的评估，以及缺乏关于睡眠和疼痛之间日常关系的数据。目前的研究利用多水平建模来比较患有慢性疼痛的青少年和健康青少年的睡眠和疼痛之间的日常联系。年龄12~18岁的青少年97人(慢性疼痛39人，健康人58人)，女性占70.1%。青少年完成10天的疼痛日记评分(0-10 NRS)和动态睡眠监测。活动睡眠变量(持续时间、效率、WASO)和自我报告的睡眠质量被测试为第二天疼痛的预测因子，白天疼痛被测试为当晚睡眠的预测因子。还测试了年龄、性别、研究组和抑郁症状对睡眠和疼痛之间日常联系的影响。多变量分析显示，夜间睡眠(p<；.001)和入睡后几分钟醒来(p<；.05)预示着第二天的疼痛，睡眠时间越长，waso越高，疼痛越严重。与假设相反，夜间睡眠质量和睡眠效率都不能预测第二天的疼痛。夜间睡眠效率和研究组之间的交互作用是显著的，与健康参与者相比，患有疼痛的青少年显示出更强的睡眠效率和第二天疼痛的相关性(p=0.05)。与假设相反，白天的疼痛并不预示着夜间的睡眠。疼痛和睡眠之间的日常联系表明，需要进一步的工作来确定干预措施中可能针对的特定青少年睡眠行为(例如，代偿性睡眠行为)。
Adolescents with chronic pain frequently report sleep disturbances, particularly short sleep duration, night wakings, and poor sleep quality. Prior research has been limited by assessment of subjectively reported sleep only and lack of data on daily relationships between sleep and pain. The current study utilized multilevel modeling to compare daily associations between sleep and pain in adolescents with chronic pain and healthy adolescents. Ninety-seven adolescents (n=39 chronic pain; n=58 healthy) aged 12–18, 70.1% female participated. Adolescents completed pain diary ratings (0–10 NRS) and actigraphic sleep monitoring for 10 days. Actigraphic sleep variables (duration, efficiency, WASO) and self-reported sleep quality were tested as predictors of next-day pain, and daytime pain was tested as a predictor of sleep that night. Effects of age, gender, study group, and depressive symptoms on daily associations between sleep and pain were also tested. Multivariate analyses revealed that nighttime sleep (p<.001) and minutes awake after sleep onset (WASO) (p<.05) predicted next-day pain, with longer sleep duration and higher WASO associated with higher pain. Contrary to hypotheses, neither nighttime sleep quality nor sleep efficiency predicted pain the following day. The interaction between nighttime sleep efficiency and study group was significant, with adolescents with pain showing stronger associations between sleep efficiency and next day pain than healthy participants (p=.05). Contrary to hypotheses, daytime pain did not predict nighttime sleep. Daily associations between pain and sleep suggest that further work is needed to identify specific adolescent sleep behaviors (e.g., compensatory sleep behaviors) that may be targeted in interventions.
登录
查看更多内容
影响因子：
3.1
作者：
Palermo, Tonya M.;Fonareva, Irina;Janosy, Norah R.
通讯作者：
Janosy, Norah R.
影响因子：
3.6
作者：
Valrie, Cecelia R.;Gil, Karen M.;Daeschner, Charles
通讯作者：
Daeschner, Charles
影响因子：
1.2
作者：
RADLOFF L S
通讯作者：
RADLOFF L S
影响因子：
2.9
作者：
Onen, SH;Onen, F;Dubray, C
通讯作者：
Dubray, C
影响因子：
5.2
作者：
Konijnenberg, AY;Uiterwaal, CSPM;Graeff-Meeder, ERD
通讯作者：
Graeff-Meeder, ERD