Measurements of insulin-mediated glucose disposal are stable over time.
Measurements of insulin-mediated glucose disposal are stable over time.
复制标题
胰岛素介导的葡萄糖处理的测量结果随着时间的推移是稳定的。
DOI：
10.1210/jcem.84.5.5662
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
G. Reaven
中科院分区：
文献类型：
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作者：
F. Facchini;M. Humphreys;J. Jeppesen;G. Reaven
To evaluate the stability of insulin-mediated glucose disposal, over time, we measured the steady-state plasma insulin (SSPI) and steady-state plasma glucose (SSPG) concentrations in response to a continuous infusion of SRIF (5 microg/min), insulin (25 microU/m2 x min), and dextrose (240 microg/m2 x min). These measurements were made in 15 healthy volunteers, studied before and after a mean (+/-SEM) interval of 48 +/- 2 months. The mean (+/-SEM) weight of the volunteers did not increase with time (75.4 +/- 3.1 vs. 76.6 +/- 3.2 kg), and there was no significant variation between the 2 mean (+/-SEM) values of either SSPI (324 +/- 18 vs. 372 +/- 24 pmol/L) or SSPG (8.4 +/- 1.0 vs. 8.2 +/- 1.0 mmol/L). Given the similarity of both SSPI and SSPG concentrations at baseline and follow-up, it can be concluded that insulin-mediated glucose disposal was stable in these 15 individuals over an interval of approximately 4 yr.
影响因子：
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作者：
BOGARDUS, C;LILLIOJA, S;REAVEN, G
通讯作者：
REAVEN, G