Erythrocytosis caused by giant chromophobe renal cell carcinoma: a case report indicating a 9-year misdiagnosis of polycythemia vera.
Erythrocytosis caused by giant chromophobe renal cell carcinoma: a case report indicating a 9-year misdiagnosis of polycythemia vera.
复制标题
巨嫌色肾细胞癌引起红细胞增多：真性红细胞增多症误诊9年一例
DOI：
10.1186/s40880-017-0238-z
复制
发表时间：
2017-09-06
影响因子：
--
通讯作者：
Ren J
中科院分区：
文献类型：
--
作者：
Guo R;Liang Y;Yan L;Xu Z;Ren J
BackgroundErythrocytosis，一种罕见的副肿瘤综合征，通常发生在透明细胞肾细胞癌患者，从来没有被报道在患者嫌色肾细胞carcinoma.Case presentationWe报告的情况下，一个年轻男子患有巨大（22厘米）的质量在他的左肾。由于真性红细胞增多症的病史，该患者已接受了9年的治疗。成功施行根治性肾切除术，术后病理检查证实诊断为嫌色细胞肾细胞癌。出乎意料的是，手术后红细胞增多症的症状消失了。结论肾嫌色细胞癌可引起红细胞增多症，但确切的发病机制尚需进一步研究。在诊断真性红细胞增多症时，应考虑继发性红细胞增多，如与肾肿瘤有关的红细胞增多。
BackgroundErythrocytosis, a rare paraneoplastic syndrome, generally occurs in patients with clear cell renal cell carcinoma and has never been reported in patients with chromophobe renal cell carcinoma.Case presentationWe report a case of a young man suffering from a giant (22-cm) mass on his left kidney. Because of a history of polycythemia vera, the patient had been treated for the condition for 9 years. Radical nephrectomy was successfully performed, and the postoperative pathologic examination confirmed a diagnosis of chromophobe renal cell carcinoma. Unexpectedly, the symptom of erythrocytosis disappeared after the surgery. Further examination and analysis were performed, and we finally attributed his erythrocytosis to chromophobe renal cell carcinoma.ConclusionsChromophobe renal cell carcinoma could cause erythrocytosis, but the clear-cut mechanism needs further research. Secondary erythrocytosis such as those related with renal tumors should be taken into consideration during the diagnosis of polycythemia vera.
登录
查看更多内容
影响因子：
6.4
作者：
Mathers, ME;Pollock, AM;O'Donnell, M
通讯作者：
O'Donnell, M
影响因子：
6.6
作者：
TURINI, D;NICITA, G;VILLARI, N
通讯作者：
VILLARI, N
影响因子：
5.6
作者：
Amin, Mahul B.;Paner, Gladell P.;Moch, Holger
通讯作者：
Moch, Holger
影响因子：
2.1
作者：
Gurel, Safiye;Narra, Vamsi;Brown, Jeffrey J.
通讯作者：
Brown, Jeffrey J.
影响因子：
23.4
作者：
Leroy, X;Moukassa, D;Gosselin, B
通讯作者：
Gosselin, B