Effects of exercise training on sleep apnea: a meta-analysis.
Effects of exercise training on sleep apnea: a meta-analysis.
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DOI：
10.1007/s00408-013-9511-3
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发表时间：
2014-02
期刊：
影响因子：
5
通讯作者：
Youngstedt SD
中科院分区：
文献类型：
--
作者：
Iftikhar IH;Kline CE;Youngstedt SD
几项研究表明，有监督的运动训练对阻塞性睡眠呼吸暂停（OSA）有良好的效果。本荟萃分析旨在分析这些研究中关于成人OSA严重程度（主要结局）的数据。关注的次要结果包括体重指数（BMI）、睡眠效率、日间嗜睡和心肺功能。两名独立的评审员检索了PubMed和Embase（从成立到2013年3月6日），以确定关于监督运动训练对OSA成人影响的研究。提取了运动前和运动后的主要和次要结果数据。共有5项研究（6个队列，共入组129例研究受试者）符合入选标准。干预（运动）前后AHI平均减少的汇总估计值为-6.27起事件/h（95%置信区间[CI]-8.54至3.99; p < 0.001）。BMI、睡眠效率、埃普沃思嗜睡量表和VO 2峰值的平均变化的汇总估计值为-1.37（95% CI −2.81至0.07; p = 0.06），5.75%（95%CI 2.47-9.03; p = 0.001）、-3.3（95%CI-5.57至-1.02; p = 0.004）和3.93 mL/kg/min（95%CI 2.44-5.42; p < 0.001）。这项荟萃分析显示，运动在降低OSA患者睡眠呼吸暂停严重程度方面具有统计学显著性效果，体重变化极小。此外，运动对心肺功能、白天嗜睡和睡眠效率的显著影响表明了运动在OSA管理中的潜在价值。
Several studies have shown a favorable effect of supervised exercise training on obstructive sleep apnea (OSA). This meta-analysis was conducted to analyze the data from these studies on the severity of OSA (primary outcome) in adults. Secondary outcomes of interest included body mass index (BMI), sleep efficiency, daytime sleepiness and cardiorespiratory fitness. Two independent reviewers searched PubMed and Embase (from inception to March 6, 2013) to identify studies on the effects of supervised exercise training in adults with OSA. Pre- and postexercise training data on our primary and secondary outcomes were extracted. A total of 5 studies with 6 cohorts that enrolled a total of 129 study participants met the inclusion criteria. The pooled estimate of mean pre- to postintervention (exercise) reduction in AHI was −6.27 events/h (95 % confidence interval [CI] −8.54 to −3.99; p < 0.001). The pooled estimates of mean changes in BMI, sleep efficiency, Epworth sleepiness scale and VO2 peak were −1.37 (95 % CI −2.81 to 0.07; p = 0.06), 5.75 % (95 % CI 2.47–9.03; p = 0.001), −3.3 (95 % CI −5.57 to −1.02; p = 0.004), and 3.93 mL/kg/min (95 % CI 2.44–5.42; p < 0.001), respectively. This meta-analysis shows a statistically significant effect of exercise in reducing the severity of sleep apnea in patients with OSA with minimal changes in body weight. Additionally, the significant effects of exercise on cardiorespiratory fitness, daytime sleepiness, and sleep efficiency indicate the potential value of exercise in the management of OSA.
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影响因子：
7
作者：
Huedo-Medina, Tania B.;Sanchez-Meca, Julio;Botella, Juan
通讯作者：
Botella, Juan
影响因子：
15.8
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
DOI：
10.1164/ajrccm.157.5.9708010
发表时间：
1998-05-01
影响因子：
24.7
作者：
O'Donnell, DE;McGuire, M;Webb, KA
通讯作者：
Webb, KA
DOI：
10.1249/01.mss.0000074566.94791.24
发表时间：
2003-07-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Hong, S;Dimsdale, JE
通讯作者：
Dimsdale, JE
影响因子：
2.5
作者：
Anandam, Anil;Akinnusi, Morohunfolu;El-Solh, Ali A.
通讯作者：
El-Solh, Ali A.