Temporary and permanent signs of interhemispheric disconnection after traumatic brain injury
Temporary and permanent signs of interhemispheric disconnection after traumatic brain injury
复制标题
创伤性脑损伤后半球间断开的暂时和永久迹象
DOI：
10.1016/s0028-3932(02)00203-8
复制
发表时间：
2003
期刊：
影响因子：
2.6
通讯作者：
G. Berlucchi
中科院分区：
文献类型：
--
作者：
A. Peru;A. Beltramello;V. Moro;Lorenzo Sattibaldi;G. Berlucchi
胼胝体常因闭合性头部创伤而受损，所导致的大脑半球间通讯障碍可能因胼胝体内病变的具体位置而异。本文描述了一个单一的情况下谁遭受了严重的创伤性脑损伤导致的胼胝体后部的病变。在纵裂分离的经典症状中，左手命名障碍、左上肢意识运动障碍、左视野阅读障碍和命名障碍以及双耳分听任务中的左耳抑制在损伤后不久被观察到，但随着时间的推移完全或几乎完全恢复。在受伤后持续4年以上的唯一症状是在简单的视觉反应时间任务中交叉-非交叉差异的异常延长。这种延长与完全胼胝体损伤或发育不全受试者中观察到的延长相当。结果表明，胼胝体后体可能是介导快速视觉运动反应的一个必要的半球间通讯通道。其他症状的短暂性质的纵裂建议通过胼胝体具有不同功能的纤维的相对广泛的分散，使得它们的部分可以生存一个有限的病变，并允许半球相互作用的功能恢复。对限制性胼胝体病变后半球间分离症状的演变进行评估，可以揭示胼胝体解剖功能地形的精细和粗糙特征。
The corpus callosum is frequently damaged by closed head traumas, and the resulting deficits of interhemispheric communication may vary according to the specific position of the lesion within the corpus callosum. This paper describes a single case who suffered a severe traumatic brain injury resulting in a lesion of the posterior body of the corpus callosum. Among the classical symptoms of interhemispheric disconnection, left hand anomia, left upper limb ideomotor dyspraxia, left visual field dyslexia and dysnomia, and left ear suppression in a dichotic listening task were observed shortly after the injury but recovered completely or almost completely with the passage of time. The only symptom of interhemispheric disconnection which was found to persist more than 4 years after the injury was an abnormal prolongation of the crossed-uncrossed difference in a simple visuomotor reaction time task. This prolongation was comparable with that observed in subjects with complete callosal lesions or agenesis. The results suggest that the posterior body of the corpus callosum may be an obligatory interhemispheric communication channel for mediating fast visuo-motor responses. The transient nature of other symptoms of interhemispheric disconnection suggests a relatively wide dispersion of fibers with different functions through the callosal body, such that parts of them can survive a restricted lesion and allow functional recovery of hemispheric interactions. An assessment of the evolution in time of symptoms of interhemispheric disconnection following restricted callosal lesions may reveal fine and coarse features of the anatomo-functional topography of the corpus callosum.
影响因子：
11
作者：
BLUMBERGS, PC;JONES, NR;NORTH, JB
通讯作者：
NORTH, JB
影响因子：
4.1
作者：
Cecil, KM;Hills, EC;Lenkinski, RE
通讯作者：
Lenkinski, RE
部分连合切开术前后胼胝体传输时间。
影响因子：
1.7
作者：
Iacoboni,M;Fried,I;Zaidel,E
通讯作者：
Zaidel,E