Cumulative social risk exposure in childhood and smoking and excessive alcohol use in adulthood.

Cumulative social risk exposure in childhood and smoking and excessive alcohol use in adulthood.
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DOI:
10.1093/eurpub/ckv243
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发表时间:
2016-08
影响因子:
4.4
通讯作者:
Griffin SJ
Griffin SJ
中科院分区:
医学3区
文献类型:
--
作者:
Caleyachetty R;Khaw KT;Surtees PG;Wainwright NW;Wareham N;Griffin SJ

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研究暴露于不同领域的儿童累积社会风险与成年后吸烟和过量饮酒之间的关系。我们使用了1993-1997年间居住在英格兰的40-75岁成年人的回溯性队列研究数据(N=19466)。参与者报告了童年时期的社会风险因素(父母失业、父母滥用药物、身体虐待、母亲分居、父母离婚、被送出家)、目前的吸烟行为和饮酒。探索性四因素分析用于确定儿童社会风险的不同领域。我们根据社会风险因素的总数和特定领域的社会风险因素的总和(范围0到2或3)创建了儿童累积社会风险分数(范围从0到≥3)。使用泊松回归来检查儿童社会风险得分与成年后吸烟和过量饮酒之间的关系。儿童社会风险领域的数量与成人吸烟(男女:P<0.001)和过度饮酒(仅限男性:P<0.008)之间存在显著的线性关联。在暴露于两个或更多不适应家庭功能因素和父母分居经历的男性中,成人吸烟的流行率也增加了(p=0.032)。这些发现可能有助于为儿童早期政策和计划的设计提供参考,这些儿童暴露在多种社会风险因素中,以缩小吸烟和过量饮酒的长期差异。
To examine the association between exposure to different domains of childhood cumulative social risk and smoking and excessive alcohol use in adulthood. We used data from a retrospective cohort study of adults aged 40–75 years in 1993–1997 living in England (N= 19,466). Participants reported exposure to childhood social risk factors (parental unemployment, parental substance misuse, physical abuse, maternal separation, parental divorce, being sent away from home), current smoking behavior and alcohol intake. Exploratory tetrachoric factor analysis was used to identify different domains of childhood social risk. We created a childhood cumulative social risk scores (range 0 to ≥3) from summing the total number of social risk factors and domain specific social risk factors (range 0 to 2 or 3). Poisson regression was used to examine the associations between childhood social risk scores and smoking and excessive alcohol use in adulthood. There was a significant linear association between the number of childhood social risk domains and adult smoking (both sexes: p<0.001) and excessive alcohol use (men only: p <0.008). The prevalence of adult smoking was also increased in men who were exposed to two or more maladaptive family functioning factors and a parental separation experience (p=0.032). These findings may help inform the design of early childhood policies and programs of children exposed to multiple social risk factors in order to attenuate long-term disparities in cigarette smoking and excessive alcohol intake.
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