Mitochondrial Dynamics: Pathogenesis and Therapeutic Targets of Vascular Diseases.
Mitochondrial Dynamics: Pathogenesis and Therapeutic Targets of Vascular Diseases.
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线粒体动力学：血管疾病的发病机制和治疗靶点
DOI：
10.3389/fcvm.2021.770574
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发表时间：
2021
影响因子：
3.6
通讯作者：
Yang Y
中科院分区：
文献类型：
--
作者：
Luan Y;Ren KD;Luan Y;Chen X;Yang Y
Vascular diseases, particularly atherosclerosis, are associated with high morbidity and mortality. Endothelial cell (EC) or vascular smooth muscle cell (VSMC) dysfunction leads to blood vessel abnormalities, which cause a series of vascular diseases. The mitochondria are the core sites of cell energy metabolism and function in blood vessel development and vascular disease pathogenesis. Mitochondrial dynamics, including fusion and fission, affect a variety of physiological or pathological processes. Multiple studies have confirmed the influence of mitochondrial dynamics on vascular diseases. This review discusses the regulatory mechanisms of mitochondrial dynamics, the key proteins that mediate mitochondrial fusion and fission, and their potential effects on ECs and VSMCs. We demonstrated the possibility of mitochondrial dynamics as a potential target for the treatment of vascular diseases.
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影响因子：
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作者：
Ciarlo L;Vona R;Manganelli V;Gambardella L;Raggi C;Marconi M;Malorni W;Sorice M;Garofalo T;Matarrese P
通讯作者：
Matarrese P
Mahuang Ganjiang汤剂对小鼠在冷应激下小鼠中淋巴细胞的融合和裂变的影响。
DOI：
10.1155/2017/5132963
发表时间：
2017
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Chen L;Chen H
通讯作者：
Chen H
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影响因子：
2.6
作者：
Deng HT;Liu HL;Zhai BB;Zhang K;Xu GC;Peng XM;Zhang QZ;Li LY
通讯作者：
Li LY
影响因子：
39.3
作者：
Brock, Matthias;Samillan, Victor J.;Huber, Lars C.
通讯作者：
Huber, Lars C.
影响因子：
11.8
作者：
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通讯作者：
Nunnari, Jodi