Preoperative estimation of future remnant liver function following portal vein embolization using relative enhancement on gadoxetic acid disodium-enhanced magnetic resonance imaging.
Preoperative estimation of future remnant liver function following portal vein embolization using relative enhancement on gadoxetic acid disodium-enhanced magnetic resonance imaging.
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DOI：
10.3348/kjr.2015.16.3.523
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发表时间：
2015-05
影响因子：
4.8
通讯作者：
Ishiguchi T
中科院分区：
文献类型：
--
作者：
Sato Y;Matsushima S;Inaba Y;Sano T;Yamaura H;Kato M;Shimizu Y;Senda Y;Ishiguchi T
回顾性评价加多乙酸二钠增强磁共振（MR）成像在肝胆期的相对增强（RE）作为术前估计门静脉栓塞（PVE）患者未来残肝（FRL）功能的指标。在53例患者中，分析肝切除术前吲哚菁绿清除率（ICG-K）与RE成像的相关性（首次分析）。53例患者中有23例接受了PVE，随后在扩大肝切除术前进行了重复RE成像和ICG检查，并对其结果进行了进一步分析（第二次分析）。在磁共振成像上计算全肝功能和FRL功能分别为：RE x总肝体积（RE指数）和FRL-RE x FRL体积（Rem RE指数）。关于临床结果，对PVE患者的肝切除术后肝功能衰竭（PHLF）进行评估。在第一次分析中，吲哚菁绿清除率与RE指数相关（r = 0.365, p = 0.007）， FRL的ICG-K （ICG-Krem）与Rem RE指数强相关（r = 0.738, p < 0.001）。在第二次分析中，PVE后ICG-Krem和Rem RE指数均显著相关（r = 0.508, p = 0.013）。PVE前后Rem RE指数的改善率显著高于ICG-Krem （p = 0.014）。PHLF患者的Rem RE指数明显低于非PHLF患者（p = 0.023）。相对增强成像可用于估计PVE后的FRL功能。
To retrospectively evaluate relative enhancement (RE) in the hepatobiliary phase of gadoxetic acid disodium-enhanced magnetic resonance (MR) imaging as a preoperative estimation of future remnant liver (FRL) function in a patients who underwent portal vein embolization (PVE). In 53 patients, the correlation between the indocyanine green clearance (ICG-K) and RE imaging was analyzed before hepatectomy (first analysis). Twenty-three of the 53 patients underwent PVE followed by a repeat RE imaging and ICG test before an extended hepatectomy and their results were further analyzed (second analysis). Whole liver function and FRL function were calculated on the MR imaging as follows: RE x total liver volume (RE Index) and FRL-RE x FRL volume (Rem RE Index), respectively. Regarding clinical outcome, posthepatectomy liver failure (PHLF) was evaluated in patients undergoing PVE. Indocyanine green clearance correlated with the RE Index (r = 0.365, p = 0.007), and ICG-K of FRL (ICG-Krem) strongly correlated with the Rem RE Index (r = 0.738, p < 0.001) in the first analysis. Both the ICG-Krem and the Rem RE Index were significantly correlated after PVE (r = 0.508, p = 0.013) at the second analysis. The rate of improvement of the Rem RE Index from before PVE to after PVE was significantly higher than that of ICG-Krem (p = 0.014). Patients with PHLF had a significantly lower Rem RE Index than patients without PHLF (p = 0.023). Relative enhancement imaging can be used to estimate FRL function after PVE.
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影响因子：
9
作者：
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通讯作者：
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