Early menarche and adult major depressive disorder among Japanese women: The role of childhood traumatic experience and socioeconomic conditions in young adulthood

Early menarche and adult major depressive disorder among Japanese women: The role of childhood traumatic experience and socioeconomic conditions in young adulthood
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日本女性初潮早期和成年重度抑郁症:童年创伤经历和社会经济条件在成年初期的作用

DOI:
10.1002/pcn5.16
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发表时间:
2022
期刊:
Psychiatry and Clinical Neurosciences Report
影响因子:
--
通讯作者:
Tadashi Takeshima
Tadashi Takeshima
中科院分区:
--
文献类型:
--
作者:
Maki Umeda;Norito Kawakami;Haruki Shimoda;Karin Miyamoto;Hanako Ishikawa;Hisateru Tachimori;Tadashi Takeshima

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目的本研究的目的是检查月经初潮早期与成人抑郁症的长期影响,并评估这种关联是否可以通过童年创伤经历和成年早期的社会经济状况来解释。方法数据来自世界精神健康调查日本第二次,2013年至2015年在日本社区居民中进行的横断面调查。我们使用了20-75岁女性受访者的数据(N= 1171)。分别计算了初潮早组和非初潮早组40年内发生重度抑郁症的风险比(HR)。采用Kaplan-Meier曲线和log-rank统计分析失败率的差异。考克斯比例风险模型进行了管理的关联性严重抑郁症与初潮和早期的生活psychosocial factors.ResultsRisk为严重抑郁症的三至四倍高初潮组,和生存功能的差异是显着的(p< 0.001)。初潮早的HR为2.79(95%CI = 1.29-6.02),当在模型中加入童年创伤经历和年轻成年时的社会经济条件时略有改变(HR = 2.88,95%CI = 1.30-6.38; HR = 3.19,95%CI = 1.41-7.21)。童年创伤和成年早期的社会经济困难并不能解释这种联系。为了预防妇女抑郁症,需要解决生命早期的身体和心理社会风险因素。
AimThe aim of this study is to examine the long‐term impact of early menarche with adult depression, and to assess whether this association was explained by childhood traumatic experience and socioeconomic condition in early adulthood.MethodsThe data were derived from World Mental Health Survey Japan Second, a cross‐sectional survey conducted among Japanese community residents between 2013 and 2015. We used the data of female respondents aged 20–75 years (N= 1171). Hazard ratio (HR) of the onset of major depression up to 40 years was calculated for an early‐menarche group and a non‐early‐menarche group, respectively. Kaplan–Meier curve and log–rank statistics were used to examine the difference in failure. Cox proportional hazard models were administered for the association of major depression with early‐menarche and early‐life psychosocial factors.ResultsRisk for major depressive disorders were three to four times higher in an early‐menarche group, and the differences in survival functions were significant (p< 0.001). HR of early menarche was 2.79 (95% CI = 1.29–6.02), and was slightly changed when childhood traumatic experience and socioeconomic conditions in young adulthood were added in the model (HR = 2.88, 95% CI = 1.30–6.38; HR = 3.19, 95% CI = 1.41–7.21).ConclusionEarly menarche was significantly associated with increased risk for depression by the age of 40 years. Childhood trauma and socioeconomic hardship in early adulthood did not account for the association. Both physical and psychosocial risk factors in early life need to be addressed for preventing women's depression.
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发表时间: 2017
影响因子: 7.3
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