Optical imaging of digit topography in individual awake and anesthetized squirrel monkeys.
Optical imaging of digit topography in individual awake and anesthetized squirrel monkeys.
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DOI：
10.1007/s00221-009-1861-y
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发表时间：
2009-07
影响因子：
2
通讯作者：
Roe, Anna Wang
中科院分区：
文献类型：
--
作者：
Chen, Li Min;Friedman, Robert Mark;Roe, Anna Wang
地形图和柱状结构是皮层感觉信息处理的基础。大部分关于详细地形图和柱状结构的知识主要来自在麻醉动物身上进行的实验。为了评估地形图是否随行为需求而变化，我们在警觉的猴子中使用了内在信号光学成像来检查皮质地形图表示的空间特异性。具体而言，在同一清醒和麻醉的松鼠猴中检查了区域3b和1中相邻远端指垫代表的体模。在麻醉动物相比，我们发现更大的皮层激活尺寸在警觉动物在区域3b，激活宽度被发现重叠，甚至不相邻的数字。这可能表明，在警觉的动物中，在区域3b内的躯体位置图上存在较少的抑制。
Topographic maps and columnar structures are fundamental to cortical sensory information processing. Most of the knowledge about detailed topographic maps and columnar structure comes mainly from experiments conducted on anesthetized animals. Towards the goal of evaluating whether topographic maps change with respect to behavioral demands, we used intrinsic signal optical imaging in alert monkeys to examine the spatial specificity of cortical topographic representation. Specifically, the somatotopies of neighboring distal finger pad representation in areas 3b and 1 were examined in the same awake and anesthetized squirrel monkey. In comparison to the anesthetized animal, we found larger cortical activation sizes in the alert animal in area 3b, where activation widths were found to overlap with even non-adjacent digits. This may suggest that in the alert animal, there is less inhibition across the somatotopic map within area 3b.
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影响因子：
56.9
作者：
AHISSAR, E;VAADIA, E;ABELES, M
通讯作者：
ABELES, M
影响因子：
2.5
作者：
Friedman, Robert M.;Chen, Li Min;Roe, Anna W.
通讯作者：
Roe, Anna W.
影响因子：
2.9
作者：
JIANG, W;LAMARRE, Y;CHAPMAN, CE
通讯作者：
CHAPMAN, CE
影响因子：
2.5
作者：
JULIANO, SL;HAND, PJ;WHITSEL, BL
通讯作者：
WHITSEL, BL
影响因子：
2.5
作者：
Chen, LM;Friedman, RM;Roe, AW
通讯作者：
Roe, AW