Polymer Mixing and the Thermodynamics of Cell Adhesion at Fluid Interfaces
Polymer Mixing and the Thermodynamics of Cell Adhesion at Fluid Interfaces
复制标题
聚合物混合和流体界面细胞粘附的热力学
DOI:
--
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发表时间:
1987
期刊:
影响因子:
--
通讯作者:
S. Schürch
中科院分区:
文献类型:
--
作者:
D. Mclver;S. Schürch
Abstract The mechanism of adhesion of cells to other cells or to non-cellular surfaces is a central problem in cell biology and biotechnology. The present studies were carried out to investigate the relationships between cell surface thermodynamics, the kinetics of cell adhesive behaviour and the molecular and morphological structure of the cell surface, when cell adhesion is elicited by defined physiological stimuli. The surface thermodynamic studies are applications of classical capillarity in which we measure the wetting of cell surfaces (the surface affinity or work of adhesion) by aqueous phase separated polymer solutions of dextran and poly (ethylene glycol), before and after exposure of the cells to the adhesive stimuli. For the phase system used here (4%/4% w/w dextran mol. wt. 2 × 106/poly (ethylene glycol) mol. wt. 2 × 104 in HEPES buffered physiological saline), the measured interfacial free energy was 4.02 × 10−6 J m−2. Isolated leukocytes were exposed to adhesion-promoting che-moattractant st...
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影响因子:
56.9
作者:
R. Snyderman;E. Goetzl
通讯作者:
R. Snyderman;E. Goetzl
DOI:
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发表时间:
1982
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Jennings,LK;Phillips,DR
通讯作者:
Phillips,DR
影响因子:
4
作者:
Hoover,RL;Folger,R;Haering,WA;Ware,BR;Karnovsky,MJ
通讯作者:
Karnovsky,MJ
DOI:
10.1016/0167-4889(82)90023-4
发表时间:
1982
期刊:
Biochimica et biophysica acta
影响因子:
--
作者:
Kaplan,HB;Edelson,HS;Friedman,R;Weissmann,G
通讯作者:
Weissmann,G