A suggested new bacteriophage genus: "Viunalikevirus".

A suggested new bacteriophage genus: "Viunalikevirus".
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DOI:
10.1007/s00705-012-1360-5
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发表时间:
2012-10
影响因子:
2.7
通讯作者:
Lavigne, Rob
Lavigne, Rob
中科院分区:
医学4区
文献类型:
--
作者:
Adriaenssens, Evelien M.;Ackermann, Hans-Wolfgang;Anany, Hany;Blasdel, Bob;Connerton, Ian F.;Goulding, David;Griffiths, Mansel W.;Hooton, Steven P.;Kutter, Elizabeth M.;Kropinski, Andrew M.;Lee, Ju-Hoon;Maes, Martine;Pickard, Derek;Ryu, Sangryeol;Sepehrizadeh, Zargham;Shahrbabak, S. Sabouri;Toribio, Ana L.;Lavigne, Rob

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我们建议一个噬菌体属,“Viunalikevirus”,作为一个新的属内的家庭Myoviridae。迄今为止,该属包括七个测序成员:沙门氏菌SFP 10和Φ SH 19;大肠杆菌CBA 120和PhaxI;志贺氏菌噬菌体phiSboM-AG 3;和Dickeya噬菌体LIMEstone 1。它们共有的肌病毒形态,具有可比的头部大小和尾部尺寸,以及基因组组织被认为是区别特征。它们似乎具有保守的调节序列、水平获得的tRNA组和DNA中胸腺嘧啶的替代碱基的可能取代。对DNA中尾刺区的仔细检查发现了四种不同的尾刺蛋白,这种排列可能导致在电子显微镜照片上可见的尾的伞状结构。这些特性使所建议的属与最近批准的Tevenvirinae亚科区分开来,尽管可以观察到显着的进化关系。本文的在线版本(doi:10.1007/s 00705 -012-1360-5)包含补充材料,可供授权用户使用。
We suggest a bacteriophage genus, “Viunalikevirus”, as a new genus within the family Myoviridae. To date, this genus includes seven sequenced members: Salmonella phages ViI, SFP10 and ΦSH19; Escherichia phages CBA120 and PhaxI; Shigella phage phiSboM-AG3; and Dickeya phage LIMEstone1. Their shared myovirus morphology, with comparable head sizes and tail dimensions, and genome organization are considered distinguishing features. They appear to have conserved regulatory sequences, a horizontally acquired tRNA set and the probable substitution of an alternate base for thymine in the DNA. A close examination of the tail spike region in the DNA revealed four distinct tail spike proteins, an arrangement which might lead to the umbrella-like structures of the tails visible on electron micrographs. These properties set the suggested genus apart from the recently ratified subfamily Tevenvirinae, although a significant evolutionary relationship can be observed. The online version of this article (doi:10.1007/s00705-012-1360-5) contains supplementary material, which is available to authorized users.
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