Feasibility and acceptability of testing a menstrual-cycle timed smoking cessation intervention for women of reproductive age (Project Phase): Results of a pilot randomized control trial.
Feasibility and acceptability of testing a menstrual-cycle timed smoking cessation intervention for women of reproductive age (Project Phase): Results of a pilot randomized control trial.
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DOI：
10.1016/j.addbeh.2021.107153
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发表时间：
2022-03
影响因子：
4.4
通讯作者：
Nair U
中科院分区：
文献类型：
--
作者：
Allen A;Skobic I;Bell ML;Medvescek K;Allen S;Collins B;Nair U
月经阶段会影响吸烟相关的结果。以电话为基础的戒烟计划(如戒烟电话)可以结合月经周期的作用，努力为妇女量身定做干预措施。这项初步的随机临床试验的目的是检验在Quiline环境下女性将戒烟日期定在月经期的可行性和可接受性。我们招募了18-40岁之间有规律月经周期的寻求治疗的女性。参与者被随机分到卵泡期(FP；戒烟日期设定在月经开始后6-8天)或标准护理阶段(SC；没有月经时间戒烟)。所有参与者都接受了四周的尼古丁替代疗法透皮贴片，同时接受了六周的电话咨询。我们调查了自我报告和生化验证的七天点患病率，治疗结束时的戒酒情况和三个月的随访。受试者(n=119；FP：n=58，SC：n=61)平均年龄33.4岁，每天吸烟13.6支。完成咨询会话的中位数为6次，66%的参与者完成了干预。超过90%的参与者表示，他们会向朋友/家人推荐这项研究。戒毒率在随机分组中没有显著差异。这项初步试验的结果表明，将戒烟日期定为FP是解决育龄妇女戒烟问题的一种可接受和可行的方法。虽然我们观察到两组之间的戒烟率相似，但这项初步研究并不能完全确定疗效。因此，可行性和可接受性结果表明，完全动力的疗效试验是必要的。
Menstrual phase influences cigarette smoking-related outcomes. Telephone-based cessation programs (e.g., quitlines) may incorporate the role of the menstrual cycle in an effort to tailor interventions for women. The goal of this preliminary randomized clinical trial was to examine the feasibility and acceptability of timing quit date to menstrual phase in women in a quitline setting. We recruited treatment-seeking women with regular menstrual cycles between the ages of 18–40 years. Participants were randomized to the follicular phase (FP; quit date set 6–8 days post onset of menses) or standard of care (SC; no menstrual timing of quit date). All participants received four weeks of nicotine replacement therapy transdermal patch concurrent with six weeks of telephone-based counseling. We explored self-reported and biochemically-verified seven-day point prevalence abstinence at end-of-treatment and three-month follow-up. Participants (n=119; FP: n=58, SC: n=61) were, on average, 33.4 years old and smoked 13.6 cigarettes/day. The median number of counseling sessions completed was 6 out of 6 available, and 66% of participants completed the intervention. Over 90% of participants reported they would recommend this study to friends/family. Cessation rates did not significantly vary by randomization. Results of this preliminary trial indicate that timing quit date to FP is an acceptable and feasible approach to address smoking cessation in women of reproductive age. While we observed similar smoking cessation rates between groups, this preliminary study was not fully powered to determine efficacy. Therefore, the feasibility and acceptability results indicate that a fully-powered efficacy trial is warranted.
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影响因子：
6
作者：
Allen, Sharon S.;Bade, Tracy;Hatsukami, Dorothy
通讯作者：
Hatsukami, Dorothy
影响因子：
4.7
作者：
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通讯作者：
Hatsukami, Dorothy
影响因子：
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通讯作者：
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影响因子：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Sofuoglu, Mehmet