Phosphoproteomics using iTRAQ.
Phosphoproteomics using iTRAQ.
复制标题
使用 iTRAQ 进行磷酸化蛋白质组学。
DOI：
10.1007/978-1-61779-264-9_17
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发表时间：
2011
影响因子：
--
通讯作者：
T. Nühse
中科院分区：
文献类型：
--
作者：
Alexandra M. E. Jones;T. Nühse
The identification of phosphorylation on proteins has become practicable for many laboratories in recent years, largely due to improvements in mass spectrometry (MS) and the development of methods to selectively enrich for phosphorylated peptides and proteins. However, phosphorylation is a dynamic and reversible modification which plays a central role in many biological processes including intracellular signalling. Therefore, the quantitative analysis of phosphorylated proteins and peptides is a subject of intense interest. We discuss three applications of isobaric tags for relative and absolute quantitation (iTRAQ) to the analysis of phosphopeptides from a variety of sample materials.
DOI：
10.1073/pnas.0404720101
发表时间：
2004-08-17
影响因子：
11.1
作者：
Beausoleil, SA;Jedrychowski, M;Gygi, SP
通讯作者：
Gygi, SP
影响因子：
4.4
作者：
Griffin, Timothy J.;Xie, Hongwei;Higgins, LeeAnn
通讯作者：
Higgins, LeeAnn