Making the most of what you've got: optimizing residual OXPHOS function in mitochondrial diseases.
Making the most of what you've got: optimizing residual OXPHOS function in mitochondrial diseases.
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DOI:
10.1002/emmm.200900049
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发表时间:
2009-11
影响因子:
11.1
通讯作者:
Moraes, Carlos T.
中科院分区:
文献类型:
--
作者:
Moraes, Carlos T.
Patients affected by mitochondrial OXPHOS disorders are still faced with a grim lack of therapeutic options. In this Closeup, Carlos Moraes revisits the recent data by Giovanni Manfredi on PKA's functions in the mitochondria and now its modulation can improve respiration and ATP production in COX-defective cells.
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