Bisphenol A: Perinatal exposure and body weight.

Bisphenol A: Perinatal exposure and body weight.
复制标题

DOI:
10.1016/j.mce.2009.02.023
复制
发表时间:
2009-05-25
影响因子:
4.1
通讯作者:
Soto AM
Soto AM
中科院分区:
医学2区
文献类型:
--
作者:
Rubin BS;Soto AM

文献摘要

参考文献

被引文献

相似文献

双酚A(BPA)是聚碳酸酯和其他塑料的一种成分,包括用于食品和饮料容器的树脂。众所周知,BPA会从与食物和饮料接触的产品中浸出,因此被认为是常规摄入。在最近的一项横断面研究中,在92.6%的美国受检人群的尿液样本中检测到BPA。体外研究表明BPA对脂肪细胞分化、脂质蓄积、葡萄糖转运和脂联素分泌的影响,表明BPA可能影响体重。来自体内研究的数据显示,在围产期暴露于BPA的啮齿动物中,对体重的影响具有剂量依赖性和性别依赖性。围产期BPA暴露对体重和肥胖产生持续影响的机制仍有待确定。BPA行动的可能目标进行了讨论。
Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from products in contact with food and drink, and is therefore thought to be routinely ingested. In a recent cross sectional study, BPA was detected in urine samples from 92.6% of the US population examined. The potential for BPA to influence body weight is suggested by in vitro studies demonstrating effects of BPA on adipocyte differentiation, lipid accumulation, glucose transport and adiponectin secretion. Data from in vivo studies have revealed dose-dependent and sex dependent effects on body weight in rodents exposed perinatally to BPA. The mechanisms through which perinatal BPA exposure acts to exert persistent effects on body weight and adiposity remain to be determined. Possible targets of BPA action are discussed.
雌激素受体ERα调节胰腺胰岛素含量。
DOI: 10.1371/journal.pone.0002069
发表时间: 2008-04-30
期刊: PLOS ONE
影响因子: 3.7
作者:
Alonso-Magdalena, Paloma;Ropero, Ana B.;Carrera, M. Pilar;Cederroth, Christopher R.;Baquie, Mathurin;Gauthier, Benoit R.;Nef, Serge;Stefani, Enrico;Nadal, Angel
通讯作者: Nadal, Angel
DOI: 10.1210/en.2005-1129
发表时间: 2006-06-01
期刊: ENDOCRINOLOGY
影响因子: 4.8
作者:
Grun, Felix;Blumberg, Bruce
通讯作者: Blumberg, Bruce
DOI: 10.1016/j.reprotox.2007.06.007
发表时间: 2007-08-01
影响因子: 3.3
作者:
Fernandez, M. F.;Arrebola, J. P.;Olea, N.
通讯作者: Olea, N.
DOI: 10.1046/j.1525-1373.2000.22402.x
发表时间: 2000-06-01
影响因子: --
作者:
Gupta, C
通讯作者: Gupta, C
DOI: 10.1074/jbc.m407539200
发表时间: 2005-04-29
影响因子: 4.8
作者:
Freedman, BD;Lee, EJ;Jameson, JL
通讯作者: Jameson, JL